2016年7月1日 · Remarkably, subunit ND1 has a five TMH repeat (TMH2–6) similar to the one of the antiporter subunits with TMH5 corresponding to the discontinuous helix of the other repeats (Fig. 3 A,B). This was predicted by homology analysis [86] and observed in bacterial and mitochondrial complex I structures [33] , [38] , [42] .

2025年1月4日 · Title: Maternally inherited non-syndromic hearing loss is linked with a novel mitochondrial ND6 gene mutation. Reduced mitochondrial-encoded NADH dehydrogenase 6 gene expression drives inflammatory CD4[+]T cells in patients with systemic lupus erythematosus.

2024年12月25日 · MT-ND6 (Mitochondrially Encoded NADH:Ubiquinone Oxidoreductase Core Subunit 6) is a Protein Coding gene. Diseases associated with MT-ND6 include Leber Hereditary Optic Neuropathy, Modifier Of and Leber Optic Atrophy And Dystonia. Among its related pathways are Complex I biogenesis and Respiratory electron transport.

2024年3月29日 · 用 lps 和 ifnγ 刺激小胶质细胞诱导野生型（wt）和 nd6 小胶质细胞中编码主要促炎细胞因子的基因表达的叠加效应，而刺激的 nd6 小胶质细胞显示出显着更高的线粒体 atp 产生。

Complex I (NADH:ubiquinone oxidoreductase) is essential foroxidative phosphorylation in mammalian mitochondria. It couples electron transfer from NADH to ubiquinone with proton translocation across...

2025年2月8日 · Reduced mitochondrial-encoded NADH dehydrogenase 6 gene expression drives inflammatory CD4 (+)T cells in patients with systemic lupus erythematosus. Pediatric-onset dystonia associated with bilateral striatal necrosis and G14459A mutation in a …

MT-ND6 is a prognostic marker in Kidney renal clear cell carcinoma Cancer specificity i Specificity of RNA expression in 17 cancer types is categorized as either cancer enriched, group enriched, cancer enhanced, low cancer specificity and not detected.

promotes GC progression by regulating mitochondrial respiratory function through the FASTK/MT-ND6 axis. Key words: Gastric cancer; Lnc-BM; FASTK; Mitochondrion Funding: National Natural Science Foundation of China (No. 82273157, 82073114, 81773383)

2024年5月6日 · 在前期研究中，我们在三阴性乳腺癌细胞中发现一种与乳腺癌脑转移相关的lncRNA，命名为Lnc-BM（long noncoding for brain metastasis），其主要定位于细胞质并具有较低的蛋白编码潜力。 通过研究，我们发现Lnc-BM通过激活JAK2-STAT3信号通路，促进下游细胞黏附分子1（intercellular adhesion molecule 1, ICAM1）和趋化因子配体2（C-C motif chemokine ligand 2, CCL2）的表达。

基因简介 中英文全称：NADH 脱氢酶亚基6 NADH dehydrogenase subunit 6 分布：线粒体|呼吸链复合体I (见于真核生物) 活性：NADH 脱氢酶 (辅酶Q)|氧化还原酶 参与：线粒体电子传 递, NADH 辅酶Q ... 对本文您有什么看法？ 2014-2025 © 360zhyx.com, All Rights Reserved. 转化医学网 版权所有. 基因简介 中英文全称：NADH 脱氢酶亚基6 NADH dehydrogenase subunit 6 分布：线粒体|呼吸链复合体I (见于真核生物) 活性：NADH 脱氢酶 (辅酶Q)|氧化还原酶 参与：线粒体电子传 …