2024年12月25日 · NFIB (Nuclear Factor I B) is a Protein Coding gene. Diseases associated with NFIB include Macrocephaly, Acquired, With Impaired Intellectual Development and Adenoid …

This gene is essential in embryonic development and it works together with its gene complex to initiate tissue differentiation in the fetus. NFIB has the highest concentrations in the lung, …

2017年8月1日 · Emerging evidence indicates that nuclear factor I/B (NFIB), a transcription factor required for proper development and regulation of cellular differentiation in several tissues, …

2023年8月21日 · Here we report that NFIB, a member of Nuclear Factor I (NFI) family that was initially purified in host cells to promote adenoviral DNA replication but has since mainly been...

2017年4月8日 · Emerging evidence indicates that nuclear factor I/B (NFIB), a transcription factor required for proper development and regulation of cellular differentiation in several tissues, …

2025年1月4日 · HIV-1 induced nuclear factor I-B (NF-IB) expression negatively regulates HIV-1 replication through interaction with the long terminal repeat region. Vemula SV, et al. Viruses, …

2019年1月22日 · NFIB3 is a truncated 188-amino acid protein, translated from a 1.8-kb message, that contains only the N-terminal DNA-binding domain. Northern blot analysis detected the 1.8 …

This gene has 22 transcripts (splice variants), 213 orthologues, 3 paralogues and is associated with 78 phenotypes. Ubiquitous expression in fat (RPKM 8.5), brain (RPKM 6.3) and 24 other …

Gene ID: 4781, updated on 8-Feb-2025. Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA …

Human Gene NFIB (ENST00000380953.6) from GENCODE V44 Description: Homo sapiens nuclear factor I B (NFIB), transcript variant 12, mRNA. (from RefSeq NM_001369465)

Title: Nfib promotes chondrocyte proliferation and inhibits differentiation by mildly regulating Sox9 and its downstream genes. NFIA and NFIB function as tumour suppressors in high-grade …

Emerging evidence indicates that nuclear factor I/B (NFIB), a transcription factor required for proper development and regulation of cellular differentiation in several tissues, also plays …

2020年5月11日 · Through single-cell transcriptomics, ATAC-Seq and ChIP-Seq profiling, we expose a key role for NFIB and NFIX in governing super-enhancer maintenance of the key …

A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt.

NFIB was found to bind to a transcriptional activator containing an ASD-associated intronic haplotype in the EN2 gene (Choi et al., 2012). Recognizes and binds the palindromic …

Impact of NFIB and CYP1A variants on clozapine serum concentration-A retrospective naturalistic cohort study on 526 patients with known smoking habits. The Polymorphic Nuclear Factor …

The MYB-NFIB gene fusion is the main genomic hallmark and a potential therapeutic target. Methods: Oncogenic signaling pathways were studied in cultured cells and/or tumors from 15 …

Nfib gene targeting and confirmation of Nfib null allele. We constructed a replacement-type targeting vector by replacing the most 3′ 523 bp of exon 2 and the first 177 bp of intron 2 with …

2025年2月8日 · Nfib promotes pro-metastatic neuronal gene expression programs and drives the metastatic ability of small cell lung cancer cells. Loss of Nfib expression resulted in prostatic …

Title: Nfib promotes chondrocyte proliferation and inhibits differentiation by mildly regulating Sox9 and its downstream genes. NFIA and NFIB function as tumour suppressors in high-grade …