2024年12月25日 · NFKB1 (Nuclear Factor Kappa B Subunit 1) is a Protein Coding gene. Diseases associated with NFKB1 include Immunodeficiency, Common Variable, 12, With …

The Nfkb1 and Nfkb2 proteins, p105 and p100, have dual functions in the NF-κB signaling system. They are best known as precursors of p50 and p52. The rate of processing of the …

NFKB1, a core transcription factor critical in various biological process (BP), is increasingly studied for its role in tumors. This research combines literature reviews, meta-analyses, and …

The importance of Nfkb1 function can be seen in mouse models, where Nfkb1 (-/-) mice display increased inflammation and susceptibility to certain forms of DNA damage, leading to cancer, …

High NFKB1 expression is associated with inflammatory uveal melanoma. NFKB1 rs28362491 polymorphism was significantly associated with the risk of head and neck carcinoma, …

2025年2月8日 · Wnt/beta-catenin and NFkappaB signaling synergize to trigger growth factor-free regeneration of adult primary human hepatocytes.

2018年2月23日 · This study has revealed that mutations in the NFKB1 gene are the most common monogenic cause of CVID. The authors highlight that if an NFKB1 mutation is …

The complete exon-intron structure of the 156-kb human gene NFKB1, which encodes the p105 and p50 proteins of transcription factors NF-kappa-B and I-kappa-B-gamma: implications for …

2002年6月20日 · The NF-kappa-B p50-p50 homodimer is a transcriptional repressor, but can act as a transcriptional activator when associated with BCL3. NFKB1 appears to have dual …

2025年2月8日 · Go to complete Gene record for NFKB1; Go to Variation Viewer for NFKB1 variants; Summary. This gene encodes a 105 kD protein which can undergo cotranslational …