The effect of nerve growth factor on supporting spatial memory …
2021年3月15日 · Nerve growth factor (NGF) gene therapy has been used in clinical trials of Alzheimer’s disease. Understanding the underlying mechanisms of how NGF influences...
Activation of UDP-galactose:globotriaosylceramide alpha 1-3 ...
1993年8月10日 · We measured the activities of UDP-galactose:globotriaosylceramide alpha 1-3-galactosyltransferase (alpha-GalTase) and protein kinase C (PKC) in PC12D …
神经生长因子（NGF）：一种关键的神经细胞生长调理因子
2024年4月23日 · 神经生长因子（NGF）是神经营养因子家族中的核心成员，其发现和研究始于上世纪中叶，由意大利科学家Levi-Montalcini等人率先报道。 NGF的发现，不仅为神经科学领域 …
Nerve Growth Factor: A Focus on Neuroscience and Therapy
Nerve growth factor (NGF) is the firstly discovered and best characterized neurotrophic factor, known to play a critical protective role in the development and survival of sympathetic, sensory …
Crystal structure of nerve growth factor in complex with the …
1999年9月9日 · Here we present the crystal structure of human NGF in complex with human TrkA-d5 at 2.2 Å resolution. The ligand–receptor interface consists of two patches of similar …
Nerve Growth Factor: The First Molecule of the Neurotrophin …
2021年8月28日 · Neurotrophins (NTs) are molecules regulating differentiation, maintenance, and functional plasticity of vertebrate nervous systems. Nerve growth factor (NGF) was the first to …
疼痛管理领域的重要研发方向——全人源神经生长因子（NGF）抗 …
2024年1月19日 · STSA-1001 注射液是一种重组抗 NGF 的全人源 IgG1 单克隆抗体注射液。 该抗体可以有效阻断 NGF 与其受体的结合，从而在疼痛疾病中有效抑制 NGF 信号通路，减少因 …
神经生长因子 - 百度百科
神经生长因子（nerve growth factor，NGF）能促进中枢和外周神经元的生长、发育、分化、成熟，维持神经系统的正常功能，加快神经系统损伤后的修复。 NGF广泛分布于机体各组织器官 …
Nerve growth factor signaling, neuroprotection, and neural repair
This article considers expanded roles for NGF that are associated with the dynamically regulated production of NGF and its receptors that begins in development, extends throughout adult life …
Reduced Myocardial Nerve Growth Factor Expression in …
2000年4月14日 · Norepinephrine (10 μmol/L) exposure reduced both NGF mRNA and protein expression in isolated cardiomyocytes, suggesting that myocardial NGF downregulation may …