
自然杀伤细胞 - 百度百科
自然杀伤细胞(natural killer cell,NK)是机体重要的免疫细胞,不仅与抗肿瘤、 抗病毒感染和免疫调节有关,而且在某些情况下参与超敏反应和自身免疫性疾病的发生,能够识别靶细胞、杀伤介质。
Natural killer cell - Wikipedia
Natural killer cells, also known as NK cells, are a type of cytotoxic lymphocyte critical to the innate immune system. They are a kind of large granular lymphocytes [1][2] (LGL), and belong to the rapidly expanding family of known innate lymphoid cells (ILC) and represent 5–20% of all circulating lymphocytes in humans. [3]
What Are Natural Killer Cells (NK Cells)? - Cleveland Clinic
2023年4月10日 · Natural killer cells (NK cells) are white blood cells that destroy infected and diseased cells, like cancer cells. They’re also a type of lymphocyte, like B-cells and T-cells. NK cells can destroy harmful cells in the early stages, preventing viruses and …
什么是NK细胞?关于NK细胞对人体有何作用机制? - 知乎
CRA-T大家都耳熟能详,模仿CAR-T的CAR技术,已研发出 CAR-engineered NK cell (如图c所示),其原理亦是通过在NK细胞表面嵌合肿瘤特异性抗原受体,靶向识别并摧毁肿瘤细胞。
Natural killer cell therapies - Nature
2024年2月21日 · The monoclonal-antibody-based NK therapies encompass the activation of NK cell antitumour immunity using immune checkpoint inhibitors (red antibodies) such as anti …
自然杀伤细胞 - 维基百科,自由的百科全书
自然殺手細胞 (英語: natural killer cell)或 自然杀手细胞,簡稱 NK细胞 (NK cell),是一类具有 细胞毒性 作用但不具有 T细胞 和 B细胞 受体的非特异性 淋巴细胞 [1][2]。
Functions of natural killer cells - Nature Immunology
2008年4月18日 · NK cell anatomical localization Consistent with their function as innate sentinels, NK cells are widespread throughout lymphoid and nonlymphoid tissues.
NK细胞图解(SNAPSHOT: Nnatural killer cells) - 知乎专栏
今年3月19日,生命科学领域顶级期刊《Cell》杂志发表了一篇关于NK细胞的Snapshot,用一张图总结了NK细胞的发育、分布、功能以及相关治疗方法。 图片来源:Cell 1. NK细胞的发育 在小鼠中,共同淋巴样祖细胞(commo…
Human NK cells: From development to effector functions - PMC
NK cells are the major lymphocyte subset of the innate immune system that mediates antiviral and anti-tumor responses. It is well established that they develop mechanisms to distinguish self from non-self during the process of NK cell education. ...
自然杀伤NK细胞是什么-NK细胞表面标志物-赛默飞 | Thermo …
自然杀伤(NK)细胞可选择性地溶解细胞,而无需事先活化。NK细胞属于天然淋巴细胞(ILC),天然淋巴细胞作为天然免疫系统的一部分,对于免疫监视和随后的宿主防御病毒感染和癌细胞至关重要。在人体中,自然杀伤(NK)细胞占循环淋巴细胞的8-20%;在实验室的近交系小鼠中,NK细胞占脾脏和 ...