2024年12月25日 · NME1 (NME/NM23 Nucleoside Diphosphate Kinase 1) is a Protein Coding gene. Diseases associated with NME1 include Neuroblastoma and Neuroblastoma 1. Among …

Nucleoside diphosphate kinase A is an enzyme that in humans is encoded by the NME1 gene. [5] . It is thought to be a metastasis suppressor. This gene (NME1) was identified because of its …

NME1 是原型和首次描述的转移抑制基因，编码参与核苷酸代谢的核苷二磷酸激酶 (NDPK)；两个相关的家族成员 NME2 和 NME4 也被报道为转移抑制因子。 这些蛋白质与 GTP 酶动力家族 …

NME1 was the first metastasis suppressor protein described, 1 defined as a protein with the ability to suppress the metastatic phenotype of cancer cells without having an impact on primary …

This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' …

2017年10月23日 · Several of the NME isoforms (NME1, NME5, NME7, and NME8) also exhibit a 3′–5′ exonuclease activity, suggesting roles in DNA proofreading and repair. NME1 and NME2 …

该基因和邻近的下游基因 (NME2) 的共转录产生天然存在的转录本 (NME1-NME2) ，它编码一种融合蛋白，该融合蛋白由与每个单独基因产物共享同一性的序列组成。[RefSeq 提供，2008 年 …

The metastasis suppressor protein NME1 is an evolutionarily conserved and multifunctional enzyme that plays an important role in suppressing the invasion and metastasis of tumour …

NME1 is a well-documented metastasis suppressor gene, with suppressor activity demonstrated across a wide spectrum of human cancers including melanoma and carcinomas of the breast, …

NME1 is located on chromosome 17q21 and encodes the NME1 protein, which contains 166 amino acids and functions to suppress metastasis. From: Pathology - Research and Practice, …