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NRF1 - Wikipedia
Nuclear respiratory factor 1, also known as Nrf1, Nrf-1, NRF1 and NRF-1, encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA … 展开
Nrf1 functions as a transcription factor that activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for mitochondrial respiration, and mitochondrial 展开
• Tiranti V, Rossi E, Rocchi M, DiDonato S, Zuffardi O, Zeviani M (1995). "The gene (NFE2L1) for human NRF-1, an activator involved in nuclear … 展开
• NRF1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
• FactorBook Nrf1
This article incorporates text from the United States National Library of Medicine, which is in the 展开CC-BY-SA 许可证中的维基百科文本 NRF1 Gene - GeneCards | NRF1 Protein | NRF1 Antibody
2024年12月25日 · NRF1 (Nuclear Respiratory Factor 1) is a Protein Coding gene. Diseases associated with NRF1 include Oncocytoma and Skin Carcinoma In Situ. Among its related pathways are Cellular responses to stimuli and …
Nuclear Respiratory Factor 1 (NRF-1) Controls the …
2018年8月20日 · The GC-rich NRF-1 binding motif is often associated with TATA-less promoters and found within 100 bp DNA regions around transcriptional start sites in the human genome (Virbasius et al., 1993; Xi et al., 2007).
核呼吸因子 1（NRF1）基因 | MCE - MCE-生物活性分子大师
核呼吸因子 1： 该基因编码一种蛋白质，该蛋白质可同源二聚化并充当转录因子，可激活一些调节细胞生长和呼吸、血红素生物合成以及线粒体 dna 转录和复制所需的核基因的关键代谢基因 …
NRF-1, an activator involved in nuclear-mitochondrial interactions ...
Nuclear respiratory factor 1 (NRF-1) was first discovered as an activator of the cytochrome c gene and was subsequently found to play a broader role in nuclear-mitochondrial interactions. We …
Nuclear Respiratory Factor 1 - an overview - ScienceDirect
Nuclear Respiratory Factor-1 (NRF-1) coordinates nuclear encoded respiratory chain expression with mitochondria gene transcription and replication [21]. NRF-1 recognition sites have been …
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Distinct isoforms of Nrf1 diversely regulate different …
2019年2月27日 · Nuclear factor-erythroid 2-related factor 1 (Nrf1, also called Nfe2l1) acts as a transcription factor belonging to the cap’n’collar (CNC) basic-region leucine zipper (bZIP) family, which is ...
NRF-1 promotes FUNDC1-mediated mitophagy as a
2025年3月1日 · NRF-1 protects cardiomyocytes from hypoxia-induced injury by promoting FUNDC1-mediated mitophagy. After knocking down FUNDC1 in NRF-1 overexpression cells, …
Nuclear respiratory factor 1 mediates the transcription ... - PubMed
The IDE core promoter locates within a 32-bp region, which contains three CGGCG repeats and a nuclear respiratory factor 1 (NRF-1) binding motif. Sequential mutation analysis indicates that …
跨膜转录因子Nrf1的生物学功能研究进展<sub><sup>*</sup></s…
跨膜转录因子Nrf1是CNC-bZIP家族中的重要成员,在维持细胞内氧化还原平衡、蛋白质稳态、内质网与线粒体稳定等功能中具有重要作用. 在小鼠不同的组织器官中敲除Nrf1后会导致多种疾病, …
