NSD1 Gene - GeneCards | NSD1 Protein | NSD1 Antibody
2024年12月25日 · NSD1 (Nuclear Receptor Binding SET Domain Protein 1) is a Protein Coding gene. Diseases associated with NSD1 include Sotos Syndrome and Beckwith-Wiedemann …
NSD1 - 百度百科
NSD1在胚胎早期发育中起调节作用，其表达异常与Sotos 综合症密切相关。 我们解析了NSD1催化中心与甲基供体复合物1.7 Å分辨率的三维晶体结构（图2A），并通过计算机动力学模拟了其 …
靶向组蛋白甲基转移酶NSD家族的抗肿瘤小分子抑制剂研究进展
nsd家族包括nsd1、nsd2(又称为mmset或whsc1)和nsd3(又称为whsc1l1)三个成员，在多种疾病的发生和发展中都发挥着重要作用。比如，nsd1功能突变和缺失会引起索托氏综合征，nsd2的 …
NSD1: A Lysine Methyltransferase between Developmental …
Recurrent epigenomic alterations associated with multiple human pathologies have increased the interest in the nuclear receptor binding SET domain protein 1 (NSD1) lysine …
NSD1 supports cell growth and regulates autophagy in HPV
2024年2月13日 · NSD1 is a histone methyltransferase that catalyzes histone H3 lysine 36 di-methylation (H3K36me 2); mutations inactivating NSD1 have been linked to improved …
《爱求索》之靶点探索篇——靶向治疗中NSD 1、NSD 2、|靶向治 …
2022年9月27日 · NSD蛋白家族(nuclear receptor binding SET domain proteins)包含三个成员: NSD1、NSD2(又名MMSET或WHSC1)和NSD3(又名WHSC1L1) ，是与肿瘤发生相关的组蛋 …
NSD1 gene - MedlinePlus
The NSD1 gene provides instructions for making a protein that functions as a histone methyltransferase. Histone methyltransferases are enzymes that modify structural proteins …
NSD1 - Wikipedia
NSD1 (Nuclear receptor binding SET Domain Protein 1) [5] is a transcription coregulator protein [6] that encodes Histone Methyltransferase and is associated with Sotos syndrome [7] and …
NUCLEAR RECEPTOR-BINDING SET DOMAIN PROTEIN 1; NSD1 …
HGNC Approved Gene Symbol: NSD1. Cytogenetic location: 5q35.3 Genomic coordinates (GRCh38) : 5:177,131,798-177,300,213 (from NCBI) The androgen receptor (AR; 313700) is a …
Histone methylation mediated by NSD1 is required for the …
2023年12月26日 · Here we showed that NSD1, the methyltransferase for di-methylated lysine 36 of histone H3 (H3K36me2), controls both area and layer identities of the neocortex. Nsd1 …