There are several different cytochemical stains that are commonly used in hematopathology, one of which is the non-specific esterase (or NSE) stain. Monocytes and their precursors (promonoblasts and monoblasts) stain a pretty red color with this stain.

Neuron-specific enolase (NSE) being a cytosolic marker may be useful in this setting. NSE is by many considered nonspecific, due to the finding of this marker in tumors considered not to be of neuroendocrine origin. Our aim was to determine whether this is true and whether NSE is more specific than previously realized.

Neuron-specific enolase (NSE) being a cytosolic marker may be useful in this setting. NSE is by many considered nonspecific, due to the finding of this marker in tumors considered not to be of neuroendocrine origin. Our aim was to determine whether this is true and whether NSE is more specific than previously realized.

A high serum NSE level was shown to be a significant early predictor of poor neurological outcome in the total study population, and in near-hanging patients with cardiac arrest. To our knowledge, this is the first study to analyze the relationship between serum NSE and neurological outcome in near-hanging patients.

Alpha-naphthyl butyrate esterase, also known as nonspecific esterase (NSE), is a monocytic marker (Fig. 18.10 A). This stain is helpful in distinguishing acute leukemias with monocytic differentiation, as well as histiocytic lesions. However, lymphoblasts, erythroblasts, and megakaryoblasts may also show a few punctuate cytoplasmic-positive ...

Immunohistochemical stain of INI1 in malignant rhabdoid tumor. This lesion is characterized by loss of the SMARCB1 gene, which encodes INI1 protein. This is a highly conserved gene that is critical to chromatin maintenance.

NSE是神經及神經內分泌細胞的糖解酵素，使用作一個腫瘤標記，來觀察破壞神經內分泌細胞的疾病，可作為病情、治療偵測，對於神經母細胞瘤數據高低反應結局。 上升於87%小細胞肺癌（SCLC，NSE>35ng/mL），10%非小細胞肺癌，48%惡性黑色素瘤，20%胃、腸、乳、攝護腺癌，以及甲狀腺髓質癌、嗜鉻細胞瘤。 NSE也上升於一些良性疾病，概率約在10%，如脂肪肝、慢性肝炎、肝硬化、肺炎。 腦出血時NSE高峰在出血後1-3 天，超過20ng/mL。 心臟引起的昏 …

Nonspecific esterase (NSE) is used to identify normal and leukemic mononuclear phagocytes cytochemically. It can be demonstrated by the hydrolysis of alpha-naphthyl acetate or butyrate. NSE from leukapheresed leukemic monocytes were extracted with several types of detergent and grouped into two isoe …

2018年7月16日 · cytochemical stains are the special stains that can be performed on peripheral blood smears and bone marrow smears. They play a very important role in diagnosis, differentiation and classification of Leukemias.

2025年1月27日 · In normal tissue, most neurons and their axonal and dendritic processes stain strongly positive for Neuron Specific Enolase (NSE), with the exception of Purkinje cells. Schwann cells, cells of the adrenal medulla, and paraganglia also contain NSE.