Fluorine 18-Fluorodeoxyglucose positron emission tomography/computerized tomography (18F-FDG PET/CT) is now used as a useful imaging tool for staging, restaging and evaluation of therapy response for most cancers.

2020年3月1日 · Continued development of PET scanners has opened a new era for 18 F-NaF, and given its higher sensitivity, there have been increasing applications in imaging. In this review, we will discuss the history, technical aspects, radiobiology, and biodistribution of this tracer.

2020年4月3日 · Fluorine-18-labeled sodium fluoride (also known as 18F-NaF or sodium fluoride) is a PET radiotracer used primarily for skeletal imaging. Fluorine-18-labeled sodium fluoride is an ionic compound comprised of a single sodium atom …

2021年6月1日 · 18F-NaF PET/CT is indicated for diagnostic imaging of bone to define altered osteogenic areas of activity. It provides high-resolution, high-contrast images of the skeletal tissue and has higher sensitivity, specificity, and accuracy than conventional nuclear bone scintigraphy.

2020年5月7日 · In this brief review, we will focus on how 18 F-NaF PET has improved our pathophysiological understanding of cardiovascular calcification and how it can be used as a marker of vascular calcification, providing a useful tool that can be utilized in clinical trials investigating the prediction of both disease progression and clinical events.

18 F－NaF是一种用于探测骨骼病变的高灵敏亲骨性PET显像剂，其在体内的摄取机制类似于 99 Tc m －MDP，但具有更好的药代动力学特性，如更快的血液清除速率和更高的骨骼摄取(相当于 99 Tc m －MDP的2倍)。

2023年10月6日 · 18F-氟化钠（18F-NaF）是一种用于探测骨骼病变亲骨性PET显像剂，骨骼对18F-NaF的摄取反应了局部血流状况及骨骼重建情况。18F-NaF其在体内的摄取机制与99mTc-MDP类似，通过与骨的主要无机盐成分 羟基磷灰石晶体 发生离子交换、化学吸附及与骨组织中有

2023年9月26日 · The use of 18 F sodium fluoride (18 F-NaF) in positron emission tomography (PET/CT) is increasing. This resurgence of an old tracer has been driven by several factors, including its superior diagnostic performance over standard 99mTc-based bone scintigraphy (BS), availability of PET/CT imaging systems, a shortened examination time and an ...

2022年9月6日 · 刚刚在ESC 2022年会上发布的PRE18FFIR（Prediction of Recurrent Events With 18F-Fluoride）（NCT02278211）研究显示，应用正电子发射断层扫描（PET）示踪剂18F氟化钠作为冠状动脉斑块易损性的标记，评估近期心肌梗死患者冠状动脉斑块活性增加并不能预测所有冠状动脉事件，但 ...

18F-NaF（18氟- 氟化钠）是一种用于探测骨骼病变的PET显像剂，具有高灵敏、亲骨性，其在骨组织内的摄取原理与99m Tc -MDP相类似，主要通过取代羟基磷灰石晶体中的羟基基团并共价结合于新骨表面，但比99m Tc -MDP 具有更好的药代动力学特性，如血液清除速率更快，并且骨组织摄取分数更高，因此灵敏度和图像质量更高。 PET/CT 作为一种将功能与解剖影像相融合的分子影像学设备，结合同机CT 提供的解剖信息， 18F-NaF PET/CT骨显像能清楚显示转移病灶部位。 …