NCK1 - Wikipedia
Nck1 regulates the activation of IRE1alpha within the pathway and when removed from the pathway disrupts activation. This means that Nck1 has an interaction with the UPR and that a …
NCK1 Gene - GeneCards | NCK1 Protein | NCK1 Antibody
2024年12月25日 · NCK1 (NCK Adaptor Protein 1) is a Protein Coding gene. Diseases associated with NCK1 include Wiskott-Aldrich Syndrome and Vaccinia. Among its related pathways are …
NCK1 NCK adaptor protein 1 [ (human)] - National Center for ...
Nck1 is an adaptor protein composed of 3 N-terminal SH3 domains followed by a unique Cterminal SH2 domain. It plays a role in cell migration, cell adhesion, actin polymerization, …
NCK1 NCK adaptor protein 1 [ Homo sapiens (human) ]
2024年12月10日 · Title: NCK1-AS1 promotes the progression of lung squamous cell carcinoma through transcriptionally upregulating NCK1 via interacting with MYC. Cooperative Interaction …
Sinner or Saint?: Nck Adaptor Proteins in Vascular Biology
2021年5月25日 · The Nck1 gene localizes to chromosome 3q21 in a region mutated in various cancers (Chen et al., 1998), and genome-wide association studies (GWAS) link Nck1 single …
NCK 衔接蛋白 1（NCK1）基因 | MCE - MCE-生物活性分子大师
由该基因编码的蛋白质是含有 Src 同源性 2 和 3 (SH2 和 SH3) 结构域的信号转导和转化蛋白质之一。 它位于细胞质中，是一种衔接蛋白，参与将信号从受体酪氨酸激酶转导至下游信号受 …
Selective role of Nck1 in atherogenic inflammation and plaque …
Nck1 mediates disturbed flow–induced endothelial activation in vivo. Having shown that Nck1 regulates endothelial activation by atheroprone flow in vitro, we sought to investigate the …
Adapting to change: resolving the dynamic and dual roles of NCK1 …
2024年10月16日 · Adaptor proteins play central roles in the assembly of molecular complexes and co-ordinated activation of specific pathways. Through their modular domain structure, the …
Nck1 is a critical adaptor between proatherogenic blood flow ...
2020年7月7日 · In this issue of the JCI, Alfaidi et al. used mouse models to explore flow-induced endothelial activation. The authors revealed a role for Nck1 and a specific activator of the …
NCK1 蛋白, Human (His) | MCE - MCE-生物活性分子大师
NCK1 protein is an adapter protein that binds to tyrosine phosphorylated receptors (KDR, PDGFRB) and cellular substrates and plays a key role in the dephosphorylation of EIF2S1 by …