2018年6月27日 · To investigate the fidelity of canonical non-homologous end joining (C-NHEJ), we developed an assay to detect EJ between distal ends of two Cas9-induced chromosomal breaks that are joined without...

To investigate the fidelity of canonical non-homologous end joining (C-NHEJ), we developed an assay to detect EJ between distal ends of two Cas9-induced chromosomal breaks that are joined without...

2022年6月27日 · We have examined EJ of chromosomal blunt DNA double-strand breaks (DSBs), and found that DNAPKcs is significantly less important than XLF for such EJ. However, weakening XLF via disrupting...

Plasmid pCMV6-AC EJ7-GFP from Dr. Jeremy Stark's lab contains the insert EJ7-GFP variant of EGFP and is published in Nat Commun. 2018 Jun 27;9(1):2484. doi: 10.1038/s41467-018-04867-5. This plasmid is available through Addgene.

gh conductivity of the conductive polymer. As a result of it, NeoCapacitor® can handle higher ripple current so that it can provide excellent performance for voltage smoothing and noise …

We welcome papers both on applied and innovative aspects and developments in nuclear science and technology. Fundamentals of Reactor Design include: Aspects beyond fundamentals of Reactor Design covered: Applications of Nuclear Energy: "nuclear-space", nuclear-transportation (ships and not only) .

2021年10月7日 · Beginning with HEK293 cells with the EJ7-GFP reporter, examined several we knockout (KO) cell lines and found that there was a significant decrease in No Indel EJ in PRKDC-KO, XLF-KO,

2020年1月3日 · In the EJ7-GFP reporter, the GFP coding sequence has been disrupted by inserting a 46-nt spacer between the first two bases (GG) and the final base (C) of the codon for glycine 67 (Fig. 6 c). We use sgRNAs to target two Cas9-induced DSBs to precisely excise the 46-nt spacer, such that No Indel EJ between the distal DSBs restores the GGC codon ...

Chromosomal EJ repair can occur by either canonical non-ho-mologous EJ (C-NHEJ) or alternative EJ (Alt-EJ) (9–12). The C-NHEJ pathway involves the core factors KU (KU70/KU80), DNA-PKcs, XRCC4, XLF, and DNA ligase IV (LIG4) (10, 11).

2024年9月1日 · Find many great new & used options and get the best deals for 10pcs 25V 22uF 22MFD D case EJ7 Tantalum Capacitors 7.3mm×4.3mm NEC KEMET TOKIN at the best online prices at eBay! Free shipping for many products!