Neonatal Lupus Erythematosus - StatPearls - NCBI Bookshelf
2023年6月26日 · Neonatal lupus erythematosus is an autoimmune disease that takes place due to the passive maternal transfer of autoantibodies of Sjogren syndrome autoantigen type A (Ro/SSA) or B (La/SSB) to the fetus.
Neonatal Lupus (NL): Symptoms & Causes - Cleveland Clinic
2024年4月22日 · Neonatal lupus is a condition that occurs when certain antibodies pass from a pregnant person to their fetus through the placenta. These antibodies attack healthy tissues and may cause heart damage. If you test positive for antinuclear antibodies (ANAs), there’s a chance your baby will develop neonatal lupus. Monitoring during pregnancy is vital.
What is neonatal lupus? - Lupus Foundation of America
Neonatal lupus is not true lupus. It is a rare condition associated with anti-SSA/Ro and/or anti-SSB/La antibodies from the mother that affect the fetus. At birth, the baby may have a skin rash, liver problems, or low blood cell counts, but these symptoms typically disappear completely after six months with no lasting effects.
Neonatal lupus erythematosus - DermNet
What is neonatal lupus erythematosus? Neonatal lupus erythematosus (LE) is a rare immune-mediated disease particularly affecting the skin and/or heart of a newborn baby with a mother positive for anti-SSA (Ro), anti-SSB (La), or anti-U1RNP antibodies. Who gets neonatal lupus erythematosus?
Neonatal lupus erythematosus - Wikipedia
Neonatal lupus erythematosus is an autoimmune disease in an infant born to a mother with anti-Ro/SSA and with or without anti-La/SSB antibodies. [1] [2] The disease most commonly presents with a rash resembling subacute cutaneous lupus erythematosus and can have systemic abnormalities such as complete heart block or hepatosplenomegaly. [3]
Neonatal lupus: Symptoms, causes, and treatment - Medical News Today
2022年10月25日 · Neonatal lupus, also known as neonatal lupus erythematosus, congenital heart block, or neonatal lupus syndrome, is a rare, acquired autoimmune disorder that a pregnant individual passes...
Neonatal Lupus Erythematosus - PMC
Neonatal lupus erythematosus (NLE) refers to a clinical spectrum of cutaneous, cardiac, and systemic abnormalities observed in newborn infants whose mothers have autoantibodies against Ro/SSA and La/SSB. The condition is rare and usually benign and self-limited but sometimes may be associated with serious sequelae.
A review of neonatal lupus syndrome - PMC
Neonatal lupus syndrome (NLS) is a condition wherein maternal autoantibodies lead to clinical symptoms in the fetus and neonate that resemble those of systemic lupus erythematosus (SLE).
Neonatal lupus: Epidemiology, pathogenesis, clinical ... - UpToDate
Neonatal lupus (NL) is an autoimmune disease in which passive transfer of autoantibodies from the mother to the fetus results in fetal and neonatal disease. The major manifestations are cardiac and cutaneous findings.
Neonatal Systemic Lupus Erythematosus Syndrome: a
2018年12月7日 · Neonatal lupus erythematosus is an uncommon syndrome, which is caused by transplacental passage of maternal autoantibodies to Sjögren's syndrome A or B autoantigens. The clinical presentation includes distinctive cutaneous lesions resembling those seen in systemic lupus erythematosus, hepatobiliary …