The neuregulin family includes: Neuregulin 1 (NRG1), with numerous discovered isoforms stemming from alternative splicing: Type I NRG1; alternative names: Heregulin, NEU …

Neuregulin-1 (NRG-1), a cardioactive growth factor released from endothelial cells, is necessary for cardiac development, structural maintenance, and functional integrity of the heart.

2003年3月10日 · The neuregulins (NRGs) are cell-cell signaling proteins that are ligands for receptor tyrosine kinases of the ErbB family. The neuregulin family of genes has four …

2008年5月14日 · Nature Reviews Neuroscience - Polymorphisms in the genes that encode neuregulin 1 (NRG1) and its receptor ErbB4 have been associated with schizophrenia. Mei …

2024年12月25日 · NRG1 (Neuregulin 1) is a Protein Coding gene. Diseases associated with NRG1 include Schizophrenia 6 and Lung Cancer . Among its related pathways are Apoptotic …

Neuregulin regulates glucose and lipid homeo-stasis. An engineered fusion protein using NRG-1 and Fc domain of human IgG1 (NRG1-Fc) exhibits extended half-life in circulation and …

Neuregulins (NRGs) comprise a family of growth factors that activate ERBB receptor kinases. Mei and Nave review the role of Nrg-Erbb signaling in neural development, myelination, and …

Neuregulin 1 functions: why are there so many isoforms, and does this diversity provide insight into pathology? We face two major challenges to bridging the gap between results of human …

Neuregulins (NRGs) comprise a large family of EGF-like signaling molecules involved in cell-cell communication during development and disease. The neuregulin family of ligands has four …

2020年6月16日 · The trophic factor Neuregulin 1 (NRG1, also called heuregulin1 or neu differentiation factor) activates signaling cascades, which regulate inhibitory neural processes …