Additionally, neuroanatomical changes are seen in the brain of patients with schizophrenia. These changes are seen in the prefrontal, medial, and superior temporal lobes as reduced gray …

Schizophrenia is associated with structural and functional changes in the cortex, as well as in the connections between different cortical regions. Recent advances in neuroimaging technology …

2024年9月6日 · The changes in schizophrenia seem to include multiple areas of the brain, mostly focused on gray matter volume deficits. Differences are frequently reported in frontal and …

2006年8月1日 · Schizophrenia is a chronic progressive disorder that has at its origin structural brain changes in both white and gray matter. It is likely that these changes begin prior to the …

2022年9月2日 · These studies show that schizophrenia is associated with lower grey matter volumes and cortical thickness, accelerated grey matter loss over time, abnormal gyrification …

2017年3月21日 · In our selective review, we summarized recent findings from longitudinal magnetic resonance imaging studies investigating structural brain alterations and its impact on …

2023年1月5日 · We hypothesized structural and functional brain abnormalities progress throughout the illness course at different rates in schizophrenia.

Neuroimaging studies have documented brain structural changes in schizophrenia at different stages of the illness, including clinical high-risk (cHR), genetic high-risk (gHR), first-episode …

2002年6月1日 · In this article, we first overviewed neuroanatomical studies using structural magnetic resonance imaging (s-MRI), MR spectroscopy (MRS), and postmortem brains, …

2003年5月1日 · First, virtually all major brain areas and circuits in the brain have been implicated in the etiology and symptomotology of schizophrenia. This is consistent with the multiple forms …

2023年1月30日 · Several studies — discussed below — have found differences in the brains of people with and without schizophrenia. These studies indicate that schizophrenia may affect …

2024年6月12日 · Our results suggest that the Broca’s area and adjacent frontoinsular cortex may be the epicenters of neuroanatomical pathophysiology in schizophrenia. These epicenters can …

2023年5月1日 · We provide evidence for two distinct longitudinal neuroanatomical endophenotypes in schizophrenia. These endophenotypes are associated with significant …

The article is a review of the latest meta-analyses regarding the genetic spectrum in schizophrenia, discussing the risks given by the disrupted-in-schizophrenia 1 (DISC1), …

In this article, we first overviewed neuroanatomical studies using structural magnetic resonance imaging (s-MRI), MR spectroscopy (MRS), and postmortem brains, followed by …

2015年9月10日 · Statistical literature analysis finds higher neuron density in schizophrenia. Ongoing differences – neuron density increase with age is slower in schizophrenia. …

Highlights: Volumetric changes occur in certain regions of the brain of schizophrenia patients.Structural changes in the brain of schizophrenia patients are associated with the …

2024年3月29日 · Background and Objectives: Neuroimaging reveals a link between psychiatric conditions and brain structural-functional changes, prompting a paradigm shift in viewing …

4 天之前 · Within the clinical schizophrenia spectrum, schizotypy has played a prominent role in defining spectrum disorders such as schizotypal personality disorder, which has shown …

2024年12月16日 · Schizophrenia-like gene expression changes modeled in human neurons matched changes found in patients’ brains. NIH Announces Funding Awards for National Early …

2025年2月26日 · Schizophrenia might be among the most intensely studied mental illnesses. However, its causes—and the way those causes manifest in the brain—remain frustratingly …

Schizophrenia, once considered a psychological malady devoid of any organic brain substrate, has been the focus of intense neuroimaging research. Findings reveal mild but generalized …

2025年2月27日 · Schizophrenia is a complex mental health condition that affects perception, thought and emotions. This complexity is reflected in the individual manifestations of the …

Our findings represent a novel approach to studying the progression of brain abnormalities in patients with schizophrenia. On a broader scale, analyzing the chronological pattern of brain …

3 天之前 · Schizophrenia is a severe, progressive mental disorder impacting roughly 1% of individuals worldwide, often emerging during the most productive life phase of 15–35 years …