Neuroligin (NLGN), a type I membrane protein, is a cell adhesion protein on the postsynaptic membrane that mediates the formation and maintenance of synapses between neurons. …

2008年10月15日 · Neurexins and neuroligins are synaptic cell-adhesion molecules that connect presynaptic and postsynaptic neurons at synapses, mediate signalling across the synapse, …

神经连接蛋白Neuroligins (NLs)是突触后膜细胞黏附分子，其连接突触前和突触后神经元，介导突触间信号的传递，并通过特定的突触功能塑造神经网络的特性。 笔者就NLs的构成、类型、功 …

Here, we review research on one major family of postsynaptic adhesion molecules, neuroligins, which bind to their presynaptic partner neurexin across the synaptic cleft. We move from a …

2022年9月10日 · Neuroligins are postsynaptic cell adhesion molecules that are relevant to many neurodevelopmental disorders. They are differentially enriched at the postsynapse and interact …

兴奋性突触后膜通过神经钙粘素 Ephrin 配体及其受体 (EphR) 与结合伴侣/细胞黏附分子 Neurexin、Neuroligin 1 和 3 之间的相互作用跨突触桥接突触前膜。 这些分子共同使突触间隙 …

2016年2月16日 · 大量研究表明 Neuroligin (NLG)1 对突触的发育和功能很重要，但是其内在机制尚不清楚。 已知在某些方面 NLG1 的功能不依赖突触前的 neurexin ，另外， NLG1 可以被活性 …

2017年11月9日 · The neuroligin family cell adhesion proteins NL1, NL2, and NL3, which are expressed by cortical astrocytes, control astrocyte morphogenesis through interactions with …

Neuroligins (NLG) are a family of transmembrane adhesion proteins implicated in ASD and ID (Bourgeron, 2015). The different neuroligin isoforms are located on the autosome (NLGN1, …

The neuroligins are cell adhesion proteins whose extracellular domain belongs to the α/β-hydrolase fold family of proteins, mainly containing enzymes and exemplified by …