NFAT and NF-kappaB factors-the distant relatives - PubMed
NFAT and NF-kappaB proteins are members of a superfamily of transcription factors whose activity plays a crucial role in the activation, proliferation and apoptosis of lymphocytes. Both …
Physical interactions between Ets and NF-kappaB/NFAT proteins …
In the studies described in this report, we demonstrated a physical interaction between multiple Ets and NF-kappaB/NFAT proteins both in vitro and in activated normal human T cells. This …
NFAT and NF-κB dynamically co-regulate TCR and CAR signaling …
2023年6月23日 · Here, we show that two key pathways in T cell signaling, calcium/nuclear factor of activated T cells (NFAT) and protein kinase C (PKC)/nuclear factor κB (NF-κB), integrate …
Interaction Between NFκB and NFAT Coordinates Cardiac …
2012年3月8日 · We identified a novel transcriptional regulatory mechanism whereby NFκB and NFAT directly interact and synergistically promote transcriptional activation in cardiomyocytes. …
Bridging the NFAT and NF-kappaB families: NFAT5 dimerization
Like Rel/NF-kappaB proteins but unlike the calcium-regulated NFAT proteins, NFAT5 is constitutively dimeric, and dimerization is essential for DNA binding and transcriptional activity. …
一文搞定|活化的T细胞核内因子 (NFAT)的结构及其功能 - 知乎
活化的T细胞核内因子（Nuclear Factors of activated T cells， NFAT）是一类 转录因子 家族，最初是在活化的T细胞中作为一种能够结合在人白介素-2（Interleukin-2，IL-2）的启动子上的快 …
一文搞定|活化的T细胞核内因子 (NFAT)的结构及其功能
2024年6月27日 · 活化的T细胞核内因子（Nuclear Factors of activated T cells， NFAT）是一类转录因子家族，最初是在活化的 T 细胞中作为一种能够结合在人白介素 - 2（Interleukin-2， IL …
PolyADP-Ribosylation of NFATc3 and NF-κB Transcription Factors …
2020年10月12日 · Recently, we have shown a pivotal role for the nuclear factor of activated T-cell cytoplasmic member 3 (NFATc3) transcription factor in modulating pulmonary macrophage …
NFAT - Wikipedia
Nuclear factor of activated T-cells (NFAT) is a family of transcription factors shown to be important in immune response. One or more members of the NFAT family is expressed in most cells of …
Interaction between NFκB and NFAT Coordinates Cardiac …
2012年4月4日 · To determine the potential functional interaction between NFAT and NFκB signaling pathways in cardiomyocytes and its role in cardiac hypertrophy and remodeling. …