Nicotinic agonist - Wikipedia
A nicotinic agonist is a drug that mimics the action of acetylcholine (ACh) at nicotinic acetylcholine receptors (nAChRs). The nAChR is named for its affinity for nicotine. Examples include …
Nicotinic Agonists - DrugBank Online
Drugs that bind to and activate nicotinic cholinergic receptors (RECEPTORS, NICOTINIC). Nicotinic agonists act at postganglionic nicotinic receptors, at neuroeffector junctions in the …
Nicotinic Agonist - an overview | ScienceDirect Topics
The medications now available for the treatment of tobacco dependence include various forms of nicotinic receptor agonists, the dopaminergic-noradrenergic reuptake inhibitor (DNRI), …
Cholinergic Drugs I - Nicotinic and Muscarinic Receptors
Some cholinergic drugs, such as muscarine, pilocarpine, and arecoline, mimic the activity of acetylcholine in stimulating the parasympathetic nervous system. These drugs, however, have …
Nicotinic Agonists and Antagonists - SpringerLink
Since most (partial) agonists are more potent in desensitizing than activating the nAChRs (see section “Pharmacologic properties of neuronal nicotinic acetylcholine receptors”), an …
14.4C: Agonists, Antagonists, and Drugs - Medicine LibreTexts
The nicotinic acetylcholine receptor agonists are gaining increasing attention as drug candidates for multiple central nervous system disorders such as Alzheimer’s disease, schizophrenia, …
Nicotinic receptors: allosteric transitions and therapeutic
Nicotinic receptors — a family of ligand-gated ion channels that mediate the effects of the neurotransmitter acetylcholine — are among the most well understood allosteric membrane …
Nicotinic Agonist - an overview | ScienceDirect Topics
A nicotinic agonist is a substance that binds to the same receptor site as acetylcholine and promotes the protein to adopt an open conformation, leading to the activation of the receptor. …
Nicotine: Uses, Interactions, Mechanism of Action - DrugBank …
2015年12月2日 · Nicotine is a stimulant drug that acts as an agonist at nicotinic acetylcholine receptors. These are ionotropic receptors composed up of five homomeric or heteromeric …
Nicotinic Agonists and Antagonists - SpringerLink
2015年1月1日 · In this update of “Nicotinic Agonists and Antagonists” (Rollema et al. 2010), we briefly describe the current knowledge of nAChRs and discuss nicotinic ligands with …