Berdazimer gel, 10.3% (SB206; Novan Inc) is a novel, topical nitric oxide–releasing agent under investigation as a first-in-class therapy for the treatment of MC.

2023年9月1日 · This reaction releases nitric oxide, relaxing the smooth muscle tissue inside the penis and increasing blood flow that is needed to obtain an erection. Clinical trials found that 65% of men who used MED3000 achieved an erection within 10 minutes and maintained it long enough to have sex.

Berdazimer is a first-in-class nitric oxide (NO)-releasing topical treatment under evaluation for use in acne and molluscum contagiosum. What is berdazimer used for? Berdazimer 10.3% gel is currently being reviewed by the FDA for the treatment of molluscum contagiosum .

2022年8月1日 · Objective: To assess the efficacy and safety of berdazimer gel, 10.3%, a novel topical nitric oxide-releasing medication, in the treatment of MC. Design, setting, and participants: This was a multicenter, vehicle-controlled, double-blind, phase 3 randomized clinical trial (B-SIMPLE4) conducted in 55 clinics (mostly dermatology and pediatric) in ...

2024年4月1日 · Berdazimer, a nitric oxide (NO)-releasing agent, treats topical molluscum contagiosum [22]. Comprising a polymeric substance with a polysiloxane backbone and covalently bound N-diazeniumdiolate nitric oxide (NO) suppliers, Berdazimer incorporates a hydrogel to facilitate targeted drug delivery through proton donor action on the skin [20].

2018年1月9日 · The oily, colourless liquid that is prepared using nitroglycerine has been found to work 12 times faster that Viagra. It also acts by releasing nitric oxide gas or NO.

2023年9月18日 · Currently, several treatment options are available for MC, including the newly investigated nitric oxide-releasing berdazimer gel, leading this review to evaluate randomized controlled trials (RCT) comparing berdazimer gel with a vehicle for treating MC.

2024年2月27日 · Berdazimer topical gel, 10.3% (ZELSUVMI™) is a nitric oxide (NO) releasing topical gel developed by Novan Inc. (a Ligand Pharmaceuticals company) for the treatment of molluscum contagiosum (MC). Novan has used their proprietary NO-based technology platform (NITRICIL™), which stores gaseous NO species on large polymers, in the development of ...

Berdazimer gel, a novel topical nitric oxide–releasing medication, appears to demonstrate favorable efficacy and safety in patients with MC who are 6 months or older. Molluscum contagiosum (MC) is a highly contagious skin condition.

Berdazimer gel, 10.3%, a potential first-in-class topical antiviral medication for molluscum, contains berdazimer sodium, a new molecular entity. Coadministration of berdazimer gel, 10.3% with a hydrogel (proton donor) releases nitric oxide (NO) from the berdazimer sodium macromolecule (comprising a polysiloxane backbone with covalently bound N ...