【罗工流式秘籍72】人和小鼠的NK细胞研究指标怎么选？ - 知乎
常规NK检测一般阳性指标CD49b+NK1.1+NKP46+，3者选1就可以判断NK细胞群比例，其中NK1.1在NK细胞发育的最初始阶段就开始表达，相对会检测的更全面一些。 但NK1.1 …
CD49a+CD49b+ NK cells induced by viral infection reflect an
Adoptive transfer experiments revealed that cNK cells could convert into CD49a + CD49b + NK cells following viral infection. Collectively, these results suggest that viral infection-induced …
IFN-γ induces aberrant CD49b+ NK cell recruitment through
2014年11月6日 · We demonstrated herein that IFN- γ induced a highly increased proportion of CD49b + NK cells in the uterus and peripheral blood and it induced a significantly upregulated …
Cutting Edge: Identification and Characterization of Human …
2015年3月15日 · Human intrahepatic CD49a + NK cells express killer cell Ig-like receptor and NKG2C, indicative of having undergone clonal-like expansion, are CD56 bright, and express …
CD49a Targeting Enhances NK Cell Function and Antitumor …
2025年1月9日 · Blockade of CD49a using an mAb suppressed tumor development in mice, and combination treatment with anti-PD-L1 further enhanced antitumor efficacy. Our research …
CD49a+CD49b+ NK cells induced by viral infection reflect an …
2020年4月23日 · These viral infection-induced CD49a+CD49b+ NK cells displayed an activated and mature phenotype. Moreover, compared with liver-resident NK cells and conventional NK …
病毒感染诱导的CD49a + CD49b + NK细胞反映了常规NK细胞的活 …
天然杀伤（nk）细胞是重要的先天效应物，在防御肿瘤和感染中起关键作用，并参与调节适应性免疫。最近的研究揭示了nk细胞的表型和功能异质性。
Cutting Edge: Human CD49e − NK Cells Are Tissue Resident in the …
2017年2月15日 · By CyTOF analysis, we found that lack of CD49e expression discriminates NK cells found in L-PxF samples but not in PBMCs. The CD49e − NK cells have phenotypic …
Accumulation of Tumor-Infiltrating CD49a + NK Cells …
In this study, we observed that accumulation of CD49a + tissue-resident NK cells in human hepatocellular carcinoma (HCC) was higher than in peritumoral tissues. We studied the …
田志刚、彭慧团队《Immunity》发文揭示肝脏定居NK细胞免疫负 …
2019年2月26日 · 近日，《Immunity》杂志刊登了中国科学技术大学田志刚院士和彭慧副教授课题组的最新研究成果“Liver-resident NK cells control antiviral activity of hepatic T cells via PD …
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