Normal Fundus Autofluorescence. In a normal fundus without retinal pathology, blood vessels will appear dark since blood is able to strongly absorb the blue (~488nm) or green (~514nm) light that is typically used in FAF imaging.

Fundus autofluorescence (FAF) imaging is based on the fluorescence from ocular endogenous fluorophores located in the retinal pigment epithelium and choroid, mainly lipofuscin and melanin. It is a noninvasive technique that provides information about the spatial distribution of lipofuscin/melanin and retinal pigment epithelium health status.

2015年9月15日 · While the surrounding retina appears mostly normal on the fundus photograph, FAF gives additional information by showing increased FAF intensity in a fine granular pattern extending beyond the geographic atrophy (GA) junctional zone. This pattern has been shown to increase the likelihood of GA progression.

2011年1月1日 · In normal cSLO blue-light FAF imaging (Figure 1), the optic nerve head is dark (black) due to the absence of RPE (and hence no lipofuscin) and the blood vessels are also dark due to absorption of the light by blood. In the central macular area, the FAF signal is reduced by absorption of blue light by luteal pigment.

2021年3月1日 · Fundus autofluorescence (FAF) imaging is an in vivo imaging method that allows for topographic mapping of naturally or pathologically occurring intrinsic fluorophores of the ocular fundus.

2014年4月1日 · Fundus autofluorescence (FAF), a relatively new imaging modality, focuses on the fluorescent properties of pigments in the retina to generate images that help us view various disease processes from a different perspective. It aids us in the understanding of the pathophysiology of different retinal disorders.

2018年3月27日 · Fundus autofluorescence (FAF) imaging is based on the fluorescence from ocular endogenous fluorophores located in the retinal pigment epithelium and choroid, mainly lipofuscin and melanin. It is a noninvasive technique that provides information about the spatial distribution of lipofuscin/melanin and retinal pigment epithelium health status.

Fundus autofluorescence (FAF) is a relatively new imaging technique that can be used to study retinal diseases. It provides information on retinal metabolism and health. Several different pathologies can be detected. Peculiar AF alterations can help the clinician to monitor disease progression and to better understand its pathogenesis.

2016年5月28日 · In the normal FAF pattern, diffuse AF is most intense between 5 degrees and 15 degrees from the fovea. The optic disc and retinal blood vessels have a low (dark) autofluorescent signal. Abnormal AF is classified into increased FAF (hyperautofluorescence) or decreased FAF (hypoautofluorescence) in comparison to the normal AF distribution or to ...

2022年6月14日 · the fundus camera, the normal fundus autofluorescence (FAF) image, and future directions in FAF imaging, including the principles of eye tracking, image averaging, and modified cameras (quantified FAF and spectrally resolved FAF)