Notch1, a member of the Notch family, is implicated in many types of cancer, including breast cancer (especially triple-negative breast cancer), leukemias, brain tumors, and many others. …

We demonstrate a novel interaction of the nephroblastoma overexpressed gene (NOV), a member of the CCN gene family, with the Notch signaling pathway. NOV associates with the …

The NOTCH1 gene provides instructions for making a protein called Notch1, a member of the Notch family of receptors. Receptor proteins have specific sites into which certain other …

2024年12月25日 · NOTCH1 (Notch Receptor 1) is a Protein Coding gene. Diseases associated with NOTCH1 include Aortic Valve Disease 1 and Adams-Oliver Syndrome 5 . Among its …

2002年8月16日 · We demonstrate a novel interaction of the nephroblastoma overexpressed gene (NOV), a member of the CCN gene family, with the Notch signaling pathway. NOV associates …

作者团队通过不同实验方法验证了神经胶质瘤起始细胞 (GICs) 中完整的 Notch1-CXCR4-PI3K 信号通路，证明了 Notch1 通过调节趋化因子系统 CXCL12/CXCR4，促进胶质瘤起始细胞的侵袭 …

2002年9月1日 · We demonstrate a novel interaction of the nephroblastoma overexpressed gene (NOV), a member of the CCN gene family, with the Notch signaling pathway. NOV associates …

We demonstrate a novel interaction of the nephroblas-toma overexpressed gene (NOV), a member of the CCN gene family, with the Notch signaling pathway. NOV associates with the …

5 天之前 · The Notch pathway regulates many developmental and homeostatic processes in animals. This Review discusses how different modes of Notch signalling can have different …

2007年7月6日 · Although Notch inhibits osteoblastic differentiation, Nov overexpression did not increase but inhibited the transactivation of a 12xCSL-Luc reporter construct and the …