2025年1月7日 · Noxidem is an imidazopyridine derivative that acts by binding to the benzodiazepine (BZD) receptors of the GABA receptor complex resulting in neuronal hyperpolarisation, action potential inhibition, increased in chloride conductance and decreased in neuronal excitability.

Zolpidem is an imidazopyridine which preferentially binds the omega-1 receptor subtype (also known as the benzodiazepine-1 subtype) which corresponds to GABA-A receptors containing the alpha-1 sub-unit, whereas benzodiazepines non-selectively bind both omega-1 …

酒石酸唑吡坦通过选择性地与中枢神经系统的ω1-受体亚型的结合，产生药理作用，是ω1-受体亚型的完全激动剂。 小剂量时，能缩短入睡时间，延长睡眠时间，在正常治疗周期内，极少产生耐受性和成瘾性；在较大剂量时，第2相睡眠、慢波睡眠 (第3和第4相睡眠)时间延长，REM睡眠时间缩短。 1、与 丙米嗪 联用时除丙米嗪的 峰浓度 降低20%外无 药代动力学 的相互作用，但可减少警醒。 2、与 氯丙嗪 合用时也无药代动力学的相互作用，但可减少警醒和影响 精神运动 的表现。 …

简介 唑吡坦是一种GABA A受体阳性调节剂，被认为通过与含有GABA A受体的α1亚基的苯二氮卓位点结合，增加氯通道开放的频率，从而抑制神经元兴奋，从而在失眠的短期治疗中发挥其治疗作用。 唑吡坦适用于以睡眠启动困难为特征的失眠的短期治疗。 In today's day of increasing surgical volume, perioperative sleep disorders are an issue that cannot be ignored. They are an important component of perioperative brain protection.

Zolpidem tartrate is a non-benzodiazepine hypnotic of the imidazopyridine class and is available in 5 mg and 10 mg strength tablets for oral administration. Chemically, zolpidem is ...

酒石酸唑吡坦是一种非苯二氮卓类的镇静催眠药，常见的商品名有思诺思、乐坦、君乐宁、诺宾等，常见的规格是 5 mg 和10 mg。 酒石酸唑吡坦是 处方药，而且作为第二类精神药品严格管制，需要去正规医疗机构，由医生开具处方后遵医嘱服药，精神类药品不能通过互联网渠道购买。 治疗偶发性失眠症和暂时性失眠症。 专业医师开具上述适应证诊断后才可以遵医嘱使用本药，患者切勿自行选用。 使用唑吡坦治疗后发生血管性水肿的患者不应再使用该药。 已知患有先天性长QT综 …

2023年6月26日 · Noxidem (zolpidem tartrate) sublingual tablets are indicated for the short-term treatment of insomnia characterized by difficulties with sleep initiation. The clinical trials performed with Zolpidem tartrate in support of efficacy were 4-5 weeks in duration with the final formal assessments of sleep latency performed at the end of treatment.

Noxidem is a medicine available in a number of countries worldwide. A list of US medications equivalent to Noxidem is available on the Drugs.com website.

Noxidem (Noxidem tartrate oral spray) is available as a clear, colorless, and cherry flavored solution designed to be sprayed directly into the mouth over the tongue. Each metered actuation (one spray) of Noxidem delivers 5 mg of Noxidem tartrate in 100 μL.

Noxidem, the active moiety of Noxidem tartrate, is a hypnotic agent with a chemical structure unrelated to benzodiazepines, barbiturates, or other drugs with known hypnotic properties. It interacts with a GABA-BZ receptor complex and shares some of the pharmacological properties of the benzodiazepines.