Atrial natriuretic peptide (ANP) or atrial natriuretic factor (ANF) is a natriuretic peptide hormone secreted from the cardiac atria that in humans is encoded by the NPPA gene. [5] Natriuretic peptides (ANP, BNP, and CNP) are a family of hormone/paracrine factors …

2024年12月25日 · NPPA (Natriuretic Peptide A) is a Protein Coding gene. Diseases associated with NPPA include Atrial Standstill 2 and Atrial Fibrillation, Familial, 6. Among its related pathways are Gene expression (Transcription) and Cardiac conduction.

2020年5月22日 · Studies on the gene encoding ANP (NPPA) initiated the field of modern research into gene regulation in the cardiovascular system. Additionally, ANP and BNP were found to be the natural...

2025年2月8日 · The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis.

2021年1月7日 · In this issue of Circulation Research, Man et al 7 shed light into how complex regulatory landscapes are organized by dissecting the transcription regulation of the Nppa-Nppb gene cluster in the mouse genome. Nppa encodes ANP (atrial natriuretic peptide), whereas Nppb encodes BNP (B-type natriuretic peptide), both hormones secreted by the heart ...

2005年9月1日 · Expression of Nppa is an early and specific marker for the differentiating working myocardium of the atria and ventricles of the developing heart. Around the time of birth, ventricular Nppa expression is down-regulated, to be reactivated in response to a variety of cardiovascular disorders.

2015年9月10日 · Variants in the human NPPA gene, encoding the ANP precursor, are associated with hypertension, stroke, coronary artery disease, heart failure (HF) and obesity. ANP and related peptides are used as biomarkers for heart disease.

2005年9月1日 · Expression of Nppa is an early and specific marker for the differentiating working myocardium of the atria and ventricles of the developing heart. Around the time of birth, ventricular Nppa expression is down-regulated, to be reactivated in response to a variety of cardiovascular disorders.

The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic Peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to ...

2019年7月24日 · Atrial natriuretic peptide (ANP), which is encoded by the natriuretic peptide precursor A gene (NPPA), is mainly secreted by atrial cardiomyocytes, and take part in...