2025年2月5日 · Non-specific interstitial pneumonia (NSIP) is the second most common morphological and pathological pattern of interstitial lung diseases after UIP. NSIP is commonly associated with connective tissue disease (CTD), and a multidisciplinary team best decides the underlying diagnosis and management ref .

NSIP是间质性肺炎的一种类型，临床主要表现为渐进性呼吸困难和咳嗽，高分辨率CT(high resolution CT, HRCT）显示双下肺及胸膜下分布为主的对称性磨玻璃影，网状阴影和牵拉性支气管或细支气管扩张，很少或无蜂窝形成；病理学特点表现为肺间质不同程度的炎症和 ...

2 天之前 · Several key features can help to distinguish NSIP from UIP. While helpful, the differences between UIP and NSIP are often not as obvious as this figure suggests, and the difficulty lies in distinguishing the cases that lie toward the middle.

2007年12月20日 · NSIP is histologically characterized by a homogeneous, uniform pattern of cellular interstitial inflammation associated with variable degrees of fibrosis. In contrast, UIP is associated with extensive fibrosis which is temporally inhomogeneous (i.e. various lesions are of …

2007年9月7日 · 临床医师依据患者的临床表现，肺功能和hrct 检查；在开胸肺活检前，9 例患者临床诊断iip，其中第一诊断为nsip 患者6 例（66%）；第一诊断为隐原性机化性肺炎（cop）2 例；第一诊断为急性间质性肺炎（aip）；此3 例的第二诊断均为nsip。nsip 的hrct 表现有一定的 ...

4 天之前 · Learn more about the features associated with NSIP on HRCT, including ground glass opacity and reticulation with a peribronchovascular distribution.

Nonspecific interstitial pneumonia (NSIP) can be idiopathic or a manifestation of collagen vascular diseases, hypersensitivity pneumonitis and drug-induced lung disease. HRCT is the best imaging tool for characterization and assessment of disease extent.

2018年12月17日 · NSIP是间质性肺炎的一种类型，临床主要表现为渐进性呼吸困难和咳嗽，高分辨率CT(high resolution CT, HRCT）显示双下肺及胸膜下分布为主的对称性磨玻璃影，网状阴影和牵拉性支气管或细支气管扩张，很少或无蜂窝形成；病理学特点表现为肺间质不同程度的炎症和 ...

2 天之前 · This table shows several HRCT features commonly seen in patients with chronic hypersensitivity pneumonitis, UIP or IPF, and NSIP. Note the significant overlap of certain features such as reticulation and ground glass opacity, and those which are not common for …

2024年8月14日 · NSIP是第二常见的CT模式，在HRCT中NSIP主要表现为网状影（87%）、牵拉性支气管扩张/细支气管扩张（82%）、下肺叶容积缩小（77%）和磨玻璃影（GGO）（44%）。 92%的NSIP患者影像学表现以下肺异常为著，其余8%的病例中所有肺部区域均匀受累。 鉴于NSIP与UIP的影像学表现较为相似，NSIP与UIP的主要区别是胸膜下无受累、大于蜂窝程度的网状影和磨玻璃影以及直边征的存在。 另外，需要强调的一个重点是，NSIP的影像学表现可能会 …

2017年9月23日 · 间质性肺炎的磨玻璃阴影：病理基础为小叶内间质增厚，即肺泡表面的间质发生炎症，覆盖部分肺泡，使肺泡密度增高，形成磨玻璃阴影。在nsip中，这部分磨玻璃阴影代表着可逆部分，也就是说及时治疗有可能能恢复肺泡功能。

2025年3月7日 · 122 NSIP, including 43 with CTD-ILD: III: 6 months: RTX-MMF versus PBO-MMF: Concurrent RTX + MMF (63 pts) versus concurrent PBO + MMF (59 pts) I: pFVC%, II: PR-D, pDLCO%, chest HRCT, PFS: Significantly improved pFVC% and PFS in RTX group compared to PBO at 6 months. PR-D, chest HRCT and change in …

NSIP is characterized histologically by a relatively uniform pattern of cellular interstitial inflammation associated with variable degrees of fibrosis. As in UIP (usual interstitial pneumonia) it mainly involves the dependent regions of the lower lobes, but NSIP lacks the extensive fibrosis with honeycombing.

2023年12月4日 · The primary HRCT findings of NSIP are reticulation (87%), traction bronchiectasis (82%), lower lobe volume loss (77%), and GGOs (44%), the latter of which can aid in differentiating from UIP . In 92% of cases, the abnormality is lower lung predominant, whereas in 8% of cases all lung zones are equally involved. 33 Therefore, upper lobe ...

nsip是排除性诊断，需要对可能的其他疾病进行仔细临床检查排除，特别是系统性风湿病、过敏性肺炎和药物毒性。 胸部X线检查 主要是显示出较低的区域网状阴影。

2021年1月18日 · Symptoms are non-specific and include insidious onset of dyspnea and dry cough with restrictive pattern of decreased lung function and reduced gas exchange capacity. This pattern manifests as mild to moderate chronic interstitial inflammation and type II pneumocyte hyperplasia, with preservation of the lung architecture.

2020年11月1日 · “NSIP with OP overlap” pattern is a controversial finding on high-resolution computed tomography (HRCT) or surgical lung biopsy (SLB) specimens that has appeared in the morphologic domain of the IPAF criteria, and it has attracted attention [8].

BAL shows either a neutrophilic or lymphocytic alveolitis (the incidence for each being approximately 50%). Radiologically, NSIP patients noticeably have above all a ground glass appearance as the main finding on the HRCT; these are generally predominantly symmetrical and in a subpleural location.

Nonspecific interstitial pneumonia (NSIP) has variable clinical, pathologic, and radiologic manifestations. Cellular and fibrotic NSIP are the two main histologic subtypes and differ from one another in the degree of inflammation and fibrosis.

Non-specific interstitial pneumonia (NSIP) is a subtype of fibrosing interstitial lung disease. In this article, we discuss clinical, histological and ra-diological /HRCT / presentation of the disease.