2020年8月13日 · We found that the OCR (Fig. 1a, Supplementary Fig. 1a, b) and ATP production linked to respiration (Supplementary Fig. 1d) were significantly decreased up to 30–50% in AML cells from two cell...

2019年8月13日 · Here we demonstrate that cancer type is a significant predictor of tumor response to mitocan treatment, and that acute myeloid leukemias (AML) show an increased sensitivity to these drugs. We...

2018年11月29日 · Acute myeloid leukemia (AML) cells are highly dependent on oxidative phosphorylation (OxPhos) for survival and continually adapt to fluctuations in nutrient and oxygen availability in the bone marrow (BM) microenvironment. The first-in-class OxPhos inhibitor IACS-010759 (Molina, Nat. Medicine 2018) is currently in Phase 1 clinical trial in AML.

2021年4月26日 · We show here that 8-Cl-Ado in the LSC-enriched population suppressed FAO by downregulating gene expression of proteins involved in this pathway and significantly inhibited the oxygen consumption rate (OCR), an indicator of OXPHOS.

2023年6月22日 · We demonstrate that MCL1 directly binds to Hexokinase 2 (HK2) on the outer mitochondrial membrane (OMM). Overall, these results suggest that high PL and high SRC plus high basal OXPHOS levels at...

2021年10月25日 · Acute myeloid leukemia (AML) cells are highly dependent on oxidative phosphorylation (OxPhos) for survival, and they continually adapt to fluctuations in nutrient and oxygen availability in the bone marrow (BM) microenvironment.

In the rise of financial crimes, optical character recognition (OCR), in combination with machine learning (ML) algorithms, serves as a crucial tool for automating AML processes by extracting the data from documents and identifying suspicious transactions.

2023年5月30日 · Optical Character Recognition (OCR) technology, combined with AI and machine learning, offers significant benefits in enhancing AML processes. OCR can automate...

2024年1月22日 · Discover the transformative role of Optical Character Recognition (OCR) in enhancing Anti-Money Laundering (AML) and Counter-Terrorism Financing (CTF) efforts. Dive into how OCR technology streamlines KYC processes, integrates with Intelligent Document Processing (IDP), and tackles challenges in financial compliance.

Optical Character Recognition (OCR) technology, combined with AI and machine learning, offers significant benefits in enhancing AML processes. OCR can automate data extraction from documents and help financial institutions identify and report suspicious transactions. This paper explores the use of OCR in AML, discussing