This is a test guideline for testing for Acute Oral Tosxidity using the Acute Toxic Class Method.

OECD Guidelines for the Testing of Chemicals are periodically reviewed in the light of scientific progress or changing assessment practices. The original Guideline 423 was adopted in March 1996 as the second alternative to the conventional acute toxicity test, described in …

Toxic Class Method》（ OECD 423，17th December 2001）为主要参考对象，结合我国化妆品 监管政策要求、检测实验室的技术水平以及化妆品原料的特点，起草了化妆品安全技术规范

固定剂量法（oecd tg 420）：受试物按规定的剂量经口给予一组实验动物，每一步使用3只单一性别的动物(通常为雌性)。 一个步骤中动物是否存在与化合物相关的死亡率将决定下一个步骤。

2023年9月13日 · OECD guidelines 420, 423 and 425 provide information on the hazardous properties and allow the substance to be ranked and classified according to the Globally Harmonised System (GHS) for the...

Organisation for Economic Co-operation and Development. This is a test guideline for testing for Acute Oral Tosxidity using the Acute Toxic Class Method. OECD Guidelines for the Testing of Chemicals, Section 4, 2074-5788. Stanford Libraries' official online search tool for books, media, journals, databases, government documents and more.

2020年12月24日 · It provides an overview of OECD guidelines for acute oral toxicity testing, including the fixed dose procedure (Guideline 420), acute toxic class method (Guideline 423), and up-and-down procedure (Guideline 425).

2002年2月8日 · OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 423: Acute ... - OECD - Google Books. This is a test guideline for testing for Acute Oral Tosxidity using the Acute Toxic...

2013年3月1日 · In this study we determined the acute oral toxicity of MON according to Guideline 423 of the Organisation for Economic Cooperation and Development (OECD). In addition to estimation of the level of acute toxicity, the approach enables the evaluation of possible target organs and clinical symptoms.

2024年11月9日 · OECD 423. 全称：OECD TG 423：Acute Oral Toxicity - Acute Toxic ClassMethod，即急性经口毒性-急性毒性分类法。 内容：该方法旨在通过动物实验对化学品的急性经口毒性进行分类，为化学品的毒性评估和标签标识提供依据。