2023年4月17日 · We demonstrate that cationic dyes (IR780, Cy7, and Cy7.5) form stable complexes with negatively charged bacterial-OMVs, improving the dyes’ in vivo circulation and …

2023年8月14日 · 监测单次静脉注射(×1)或多次静脉注射(×3， ×5)给药的Cyanine7 (Cy7)标记的OMV在肿瘤中的积累，其中只在最后一次注射中使用 Cy7标记 的OMV。 虽然在×1组中标记 …

2025年2月14日 · In this study, bone marrow-derived mesenchymal stem cells (BMSCs) are genetically engineered to overexpress CXCR4 and isolated cell membranes (mBMSC CXCR4) …

Nevertheless, emerging evidence reflected shortcomings of native OMV in tumor therapy recently. Kim et al. labeled OMVs with Cyanine7 (Cy7) and detected different levels of OMVs …

2017年9月20日 · Cy7-labeled OMVs (10 μg in total protein) were injected intravenously to normal mice and mice bearing tumor with a diameter of 15 mm (male, 8 weeks old).

2022年5月2日 · Here we show that outer membrane vesicles (OMVs) fused to a tumour antigen and produced in the intestine by ingested genetically engineered bacteria function as effective …

We demonstrate that cationic dyes (IR780, Cy7, and Cy7.5) form stable com-plexes with negatively charged bacterial-OMVs, improving the dyes’ in vivo circulation and optoacoustic …

2023年8月15日 · 开发了一种装载PD-1质粒的LyP1多肽修饰的外膜囊泡 (LOMV)，以实现PD-L1在肿瘤细胞中的自阻断。 纳米载体通过OMV靶向能力在肿瘤组织中积累，并通过lyP1介导的靶 …

Targeting of E. coli ΔmsbB OMVs to tumor tissues after systemic administration. a Cy7 control and Cy7-labeled E. coli ΔmsbB OMVs (ΔmsbB Cy7 OMVs) were systematically injected to …

2021年4月6日 · Outer membrane vesicles (OMVs) can strongly activate the innate immune system and are qualified as immunoadjuvants. Here, we describe a versatile OMV-based …