14 小时之前 · Each OPC is a little different in terms of the services they provide versus those that they refer out, but most include some combination of the following: a safe space where people can use their own illicit drugs under the watchful eye of a healthcare provider trained to treat overdoses, sinks, showers, counselors, harm reduction training and ...

In OPCs, trained staff can use naloxone (an overdose reversal medication) and oxygen to reverse an overdose and save a life, without needing to call 911. These sites also provide new, safe supplies (pipes, cookers, etc.) to reduce the risk of infection and disease, by preventing the need to share or reuse equipment.

什么是用药过量预防中心 (overdose prevention center, OPC)？ • OPC 是人们可以在接受过培训的工作人员监督下，安全服用之前所得药物的场所。 • 纽约市 (NYC) 目前有两处 OPC 正在运营，分别位于 East Harlem 和 Washington

2023年3月13日 · The mainstays of medical therapy in organophosphate (OP) poisoning include atropine, pralidoxime (2-PAM), and benzodiazepines (eg, diazepam). Initial management must focus on adequate use of...

2023年2月28日 · Strong evidence indicates that overdose prevention centers (OPCs) reduce the transmission of HIV and hepatitis, prevent overdose deaths, reduce public injections, reduce the volume of...

Overdose prevention centers (OPCs) are a harm reduction strategy that has operated around the world for decades, though there are no OPCs operating legally in the United States. OPCs are professionally supervised facilities where persons who use drugs can consume them under controlled conditions.

3 天之前 · Another suggested unintended outcome of OPCs is the attraction of people who use drugs to the area; the so-called ‘honey pot’ effect. There are a few articles reporting increases in public nuisance after the establishment of an OPC, including drug litter and aggressive and erratic behaviour by people leaving the OPC [150,151,152].

2007年11月18日 · OPC-51803 is the first nonpeptide vasopressin (AVP) V (2)-receptor-selective agonist. It is a V (2)-selective agonist that produces a significant antidiuretic action after single and multiple oral dosing in AVP-deficient and normal AVP states.

2 天之前 · The study conducted in-depth qualitative interviews from December 2023 to March 2024 with 25 people who use drugs. Thematic analysis explored OPC implementation considerations, with a focus on perceived social and structural barriers and facilitators for use. The study shared findings iteratively with the future OPC's operating organization.

OPCs are facilities where people can use their own pre-obtained drugs, designed with the goal of reducing fatal overdoses, public drug consumption, and related outcomes. In 2022, 353 people died of an opioid overdose in Boston.