ARBs selectively block 1 of the 2 Ang II receptors, namely AT1R, thereby blocking the abnormally activated renin-angiotensin-aldosterone system. ARBs inhibit vasoconstriction, reduce peripheral vascular resistance, and inhibit aldosterone secretion, reducing water and sodium retention.

An article from the obstetrics section of Primary Care Notebook: Angiotensin II receptor blocker (ARB) and breast feeding and pregnancy. This site is intended for healthcare professionals Pages

Angiotensin converting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARBs) are known to cause fetal renal damage in pregnancy. Due to conflicting reports in the literature, their safety after first trimester exposure has been ...

Objectives: To present cases exhibiting possible effects of angiotensin II receptor blockers (ARBs) received in pregnancy on the fetus. Methods: Retrospective analysis included women who delivered between 2002 and 2006 at Department of Obstetrics and Gynaecology Ljubljana.

2009年7月1日 · To present cases exhibiting possible effects of angiotensin II receptor blockers (ARBs) received in pregnancy on the fetus. Retrospective analysis included women who delivered between 2002 and 2006 at Department of Obstetrics and Gynaecology Ljubljana. Antihypertensive medications were prescribed to 346 of the 26,735 women.

Patients inadvertently exposed to ARBs during the early pregnancy may be reassured. Nevertheless, women planning pregnancy should avoid ARBs. In selected cases, ARBs might be continued under careful monitoring of menstrual cycle a …

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ACE inhibitors and angiotensin II receptor antagonists (A2RAs) (angiotensin receptor blockers (ARBs)) use during breastfeeding. A review by the NHS Specialist Pharmacy Service noted with respect to use of A2RAs (ARBs) during breastfeeding (2):

Angiotensin II receptor blockers (ARBs) are potent antihypertensive agents that block the renin angiotensin aldosterone system (RAS). Their use in pregnancy may cause malformations, oligoanuria, hypotension, and death. Hypotension is observed up to 15% of cases and is described as refractory to volu …

2024年6月20日 · Angiotensin II receptor blockers (ARBs) are contraindicated during pregnancy because of fetal toxicity. All previous reports on adverse fetal outcomes involved women who continued to take low-dose ARBs for hypertension and were unaware of the adverse effects.