Optical coherence tomography (OCT) has emerged as a fast, non-invasive, inexpensive, high-resolution imaging technique in multiple sclerosis (MS). Retinal layer quantification by OCT facilitates a 'window' into not only local retinal pathology but also global neurodegenerative processes, recognised …

OCT is a rapid, non-invasive, office-based imaging technique providing objective quantification of retinal structures with high resolution that is an effective diagnostic tool for evaluating disease activity related to multiple sclerosis.

Optical coherence tomography has contributed to greater insights into the pathophysiology of MS. Loss of RNFL and GCIPL thickness correlates with clinical and paraclinical parameters such as biomarkers, visual function, disability and magnetic resonance imaging in MS. Some studies indicate that OCT parameters may be able to predict disability ...

Optical coherence tomography (OCT) is of increasing interest in the clinical assessment of multiple sclerosis (MS) patients beyond the scope of clinical studies. In this narrative review, we discuss novel changes of OCT parameters during acute optic ...

Optical coherence tomography (OCT) is a new method that could aid analysis of neurodegeneration in multiple sclerosis (MS) by capturing thinning of the retinal nerve fibre layer (RNFL). Meta-analyses of data for time domain OCT show RNFL thinning of 20.38 microm (95% CI 17.91-22.86, n=2063, p<0.0001) after optic neuritis in MS, and of 7.08 ...

Optical coherence tomography has contributed to greater insights into the pathophysiology of multiple sclerosis. Loss of retinal nerve fibre layer and ganglion cell layer thickness correlate with clinical and paraclinical parameters such as visual function, disability and …

The aim of this review was to highlight the most current optical coherence tomography (OCT) and optical coherence tomography angiography (OCT-A) data in MS and to provide information about the possibility of using OCT / OCT-A parameters as biomarkers for screening, diagnosis and monitoring of MS.

Optical coherence tomography (OCT) is a new method that could aid analysis of neurodegeneration in multiple sclerosis (MS) by capturing thinning of the retinal nerve fibre layer (RNFL).

2020年1月1日 · Multiple sclerosis (MS) is a chronic, currently incurable neurologic disease, which frequently affects the visual system. The development of optical coherence tomography (OCT), which facilitates the viewing of retinal neurons and axons in vivo, has enabled researchers and clinicians to better characterise the effects of MS on the retina.

2016年3月31日 · In this chapter, we summarize the data and current concepts for use of OCT in the evaluation and monitoring of patients with MS. Importantly, we will highlight how OCT has expanded our thinking about the pathogenesis of visual pathway dysfunction, and how RNFL and GCL+IPL thickness may serve as structural markers for monitoring disease in our ...