
OGDHL Gene - GeneCards | OGDHL Protein | OGDHL Antibody
2024年12月25日 · OGDHL (Oxoglutarate Dehydrogenase L) is a Protein Coding gene. Diseases associated with OGDHL include Yoon-Bellen Neurodevelopmental Syndrome and Seckel …
氧化戊二酸脱氢酶 L(OGDHL)基因 | MCE - MCE-生物活性 ...
该基因编码的蛋白质类似于 OGDH 复合物中的氧化戊二酸脱氢酶 (OGDH) ,可降解葡萄糖和谷氨酸。 该基因编码几种亚型,包括一些似乎定位于线粒体的亚型。 编码的蛋白质下调 Akt 信号 …
南京大学医学院研究者们揭示了氧化戊二酸脱氢酶诱导DNA损伤抑 …
氧化戊二酸脱氢酶(ogdhl)是氧化戊二酸脱氢酶(ogdh)复合体中降解葡萄糖和谷氨酸的同工酶。 据报道,OGDHL可以重新编程 谷氨酰胺 代谢,以酶活性依赖的方式抑制肝癌的进展。
OGDHL的机制与疾病
本综述系统地介绍了OGDHL的机制及在不同疾病中的表达情况和作用。 氧戊二酸脱氢酶样(oxoglutarate dehydrogenase-like,OGDHL)蛋白是氧戊二酸脱氢酶复合体(OGDHC)的主要 …
OGDHL is a modifier of AKT-dependent signaling and NF-κB …
Oxoglutarate dehydrogenase (OGDH) is the first and rate-limiting component of the multi-enzyme OGDH complex (OGDHC) whose malfunction is associated with neuro-degeneration. The …
Oxoglutarate dehydrogenase-like inhibits the progression of ...
2023年7月7日 · Oxoglutarate dehydrogenase-like (OGDHL) is considered to be the isoenzyme of oxyglutarate dehydrogenase (OGDH) in the OGDH complex, which degrades glucose and …
The m6A modification-mediated OGDHL exerts a tumor …
2023年8月25日 · We found that OGDHL acts as a tumor suppressor by inhibiting the proliferation, migration, and invasion of ccRCC cells. Mechanistic studies revealed that FTO inhibits …
OGDHL oxoglutarate dehydrogenase L [ (human)] - National …
2025年2月8日 · OGDHL silencing promotes hepatocellular carcinoma by reprogramming glutamine metabolism. OGDHL closely associates with tumor microenvironment and can serve …
IF>10 家系研究 | OGDHL变异导致神经发育谱系疾病,表现为癫痫 …
2-酮戊二酸脱氢酶样蛋白 (2-oxoglutarate dehydrogenase-like, OGDHL)是Krebs循环中的限速酶,在线粒体代谢中起着关键作用。 OGDHL的表达主要在人类的大脑,提示OGDHL参与了脑 …
Evaluating the association of biallelic OGDHL variants with …
2023年11月29日 · Using an unbiased genotype-first approach, we screened large, multiethnic aggregated sequencing datasets worldwide for biallelic OGDHL variants. We used …
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