Orexin (/ ɒˈrɛksɪn /), also known as hypocretin, is a neuropeptide that regulates arousal, wakefulness, and appetite. [5] . It exists in the forms of orexin-A and orexin-B.

2023年12月22日 · Orexins are neuropeptides, produced in a part of the brain called the hypothalamus. Out of the billions of cells in the brain, there are only 10,000 to 20,000 cells that …

2025年3月5日 · Orexins are neurotransmitters, which are chemicals in your brain that send messages from one neuron (a nerve cell) to another. Only a small group of neurons in the …

2024年11月6日 · Orexin, also known as hypocretin, is a neuropeptide. It plays a crucial role in regulating your sleep-wake cycle, reward and motivation, and the stress response. Orexin …

Orexins, also known as hypocretins, are two neuropeptides secreted from orexin-containing neurons, mainly in the lateral hypothalamus (LH). Orexins orchestrate their effects by binding …

Orexin neurons are “multi-tasking” neurons regulating a set of vital body functions, including sleep/wake states, feeding behavior, energy homeostasis, reward systems, cognition and …

2022年12月15日 · Orexin, also called hypocretin, is a neurotransmitter that regulates arousal, wakefulness, and appetite. Scientists suspect that narcolepsy is caused by a lack of orexin in …

Orexins (also known as hypocretins) were identified as endogenous ligands for two orphan G-protein-coupled receptors in the lateral hypothalamic area. They were initially recognized as …

Orexin A and orexin B are hypothalamic neuropeptides initially identified as endogenous ligands for two orphan G-protein coupled receptors (GPCRs). They play critical roles in the …

Orexin antagonists, especially those that block OX2 or both OX1 and OX2 receptors, clearly promote sleep in animals, and clinical results are encouraging: Several compounds are in …

2017年5月31日 · Orexin neurons are "multi-tasking" neurons regulating a set of vital body functions, including sleep/wake states, feeding behavior, energy homeostasis, reward …

Orexins are neurotransmitters which act through synaptic contacts to activate neurons involved in the central regulation of the functions listed above. Orexins are also found at low levels in the …

2014年10月10日 · Orexins play an important part in the formation of cued fear memory through activation of noradrenergic neurons in the locus coeruleus. Cues and contexts associated with …

2020年10月20日 · Orexin testing, a diagnostic procedure requiring a lumbar puncture, can detect type 1 narcolepsy in conjunction with sleep studies like MSLT. Mayo Clinic has developed a …

Orexin-A and -B (also known as hypocretin-1 and -2) are neuropeptides produced in the lateral hypothalamus that promote many aspects of arousal through the OX1 and OX2 receptors. In …

Origin OS 1.0 is based on the Android 11 operating system. It will be first installed on the Vivo X60 series and will gradually be adapted to other Vivo phones later. [8]Origin OS Ocean (2.0) …

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The orexins, also known as hypocretins, are two neuropeptides (orexin A and B or hypocretin 1 and 2) produced by a few thousand neurons located in the lateral hypothalamus that were …

2017年5月30日 · Orexin neurons are “multi-tasking” neurons regulating a set of vital body functions, including sleep/wake states, feeding behavior, energy homeostasis, reward …

2025年2月21日 · The mission patch for NS-30. Additionally, Blue Origin released the NS-30 mission patch. A few of the symbols embedded include: The mountain represents Spanish …

2025年2月13日 · Blue Origin has announced plans to lay off about 10% of its workforce — or more than 1,000 employees — nearly a month after the company debuted its first orbital …

Orexin (ORX) neurons indirectly inhibit neurons of the ventrolateral preoptic nucleus (VLPO) of the hypothalamus, which promote sleep, express gamma-aminobutyric acid (GABA) and …

2025年2月25日 · After a slight delay due to a hold, Blue Origin's suborbital New Shepard vehicle lifted off from the company's West Texas site today at 10:50 a.m. EST (1550 GMT; 9:50 a.m. …

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In 1998, de Lecea et al. 1 and Sakurai et al. 2 reported the discovery of a gene they named hypocretin and orexin, respectively, which led to a revolution in our understanding of genetic …

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Orexins are excitatory neuropeptides, which are predominantly associated with feeding behavior, sleep-wake cycle and energy homeostasis. The orexinergic system comprises of HCRTR1 …