Organochlorines are known for their high persistence and toxicity characteristics. These pesticides cause neurological damage, endocrine disorders, and have acute and chronic health effects. Hence contamination of the environment with organochlorine pesticides drastically affects the …

Organochlorine chemistry is concerned with the properties of organochlorine compounds, or organochlorides, organic compounds that contain one or more carbon–chlorine bonds. [1] The chloroalkane class (alkanes with one or more hydrogens substituted by chlorine) includes common examples. The wide structural variety and divergent chemical properties of …

Organochlorine (OC) pesticides are synthetic pesticides widely used all over the world. They belong to the group of chlorinated hydrocarbon derivatives, which have vast application in the chemical industry and in agriculture. These compounds are known for their high toxicity, slow degradation and bi …

the organochlorines are available from the Centers for Disease Control and Preven-tion’s Biomonitoring Program and may be helpful in interpreting findings.38 Lindane tissue concentration reports appear in the literature more frequently than other compounds. The time of the blood sampling in relation to exposure time must

Organochlorines are chemicals that contain carbon and chlorine. Many organochlorines are harmful because they do not break down easily. This means they stay in the environment and our bodies for a long time. They can be concentrated in the food chain so the animals at the top of the food chain, such as humans, will have the highest levels. There are 12 organochlorines listed …

1.1.2 Organochlorine pesticides. Organochlorines are one of the main subgroup of pesticides that have the ability to damage the nervous system of organisms (Walker, Hopkin, Silby, & Peakall, 2006).Organochlorine insecticides are known as highly lipophilic and persistent but they have very low water solubility. Due to long residence time and lipophilicity, these chemicals may enter …

Organochlorines comprise the pesticide class most frequently associated with PD. These include DDT, aldrin, dieldrin, endosulfan, hexachlorocyclohexanes (e.g., lindane), heptachlor, methoxychlor, chlordane, and others. Most of these compounds were commercialized in the period following WWII, and although many have been banned since the 1970s ...

2020年11月3日 · Most organochlorines act as non-competitive antagonists acting at the chlorine ion channel of GABAa receptors but DDT acts by inhibiting sodium channel closure following depolarisation. Both mechanisms are neuroexcitatory. Toxicokinetics: Rapidly absorbed following ingestion. Most are well absorbed across the skin

2023年9月15日 · Organochlorines, organophosphates, carbamates, pyrethroids, and neonicotinoids are among the most commonly used substances. According to statistics on the use of various pesticides, 40% of all pesticides are used from the organochlorine chemical family (Gupta, 2004; Lallas, 2001; Jayaraj et al., 2016).Organochlorine pesticides (OCPs) are widely …

2013年8月16日 · Organochlorines, organophosphates, carbamates, pyrethroids, thiocarbamates, triazines, and triazoles furthermore exhibit thyroid disruption properties in rodents, birds, amphibians, and fish . Immunotoxicity, which is primarily caused by the inhibition of serine hydrolases or esterases, oxidative damage, and the modulation of signal ...