2025年1月14日 · We identified OsRac1, a GTPase, as a key signalling molecule involved in Pigm-1-mediated blast resistance, suggesting that OsRac1 is a universal downstream effector for rice NLRs. Furthermore, RAI1, a transcriptional activator, emerged as a crucial Pigm-1 partner, with Pigm-1’s NBS and CC domains facilitating the activation of OsRac1 and RAI1 ...

2019年8月6日 · Here we show that the grain size and yield of rice (Oryza sativa) is positively regulated by ROP GTPase (Rho-like GTPase from plants), a versatile molecular switch modulating plant growth, development, and responses to the environment.

2025年1月14日 · This study reveals OsRac1, a GTPase, as a signalling molecule involved in Pigm-1-mediated blast resistance, suggesting its potential as a common downstream effector of rice NLR proteins. Additionally, a transcriptional activator, RAI1, acts as an essential Pigm-1 interactor for blast resistance.

OsRac1, OsRACK1A, RACK1 functions in rice innate immunity by interacting with the Rac1 immune complex, Rac1 positively regulates RACK1A at both the transcriptional and posttranscriptional levels

OsRac1是一种小GTPase，和GDP结合处于非活性状态，和GTP结合处于激活状态。前期研究表明，OsRac1可以诱导水稻对多种病原菌侵染产生免疫。说明OsRac1在植物免疫方面发挥重要作用，但是具体的分子机制仍不清楚。 科学问题. OsRac1增加水稻抗病性的分子机制是什么？

SPIN6在体外能够与小GTP酶OsRac1互作，催化GTP与OsRac1结合形成GDP结合状态，在水稻细胞中也具有作用于OsRac1的GAP活性（Liu et al., 2015）。 病原菌入侵水稻时，OsRac1能与Pit的NB-ARC结构域互作，并被激活，从而在Pit介导的免疫反应中发挥重要作用。

2019年3月28日 · We identified OsRac1, a known GTPase, as a signalling molecule in PID3-mediated blast resistance, implicating OsRac1 as a possible common factor downstream of rice NLR proteins.

2018年12月4日 · Here, we identified OsSPK1, a DOCK family guanine nucleotide exchange factor, as an interactor of Pit and activator for OsRac1. OsSPK1 contributes to signaling by two disease-resistance genes, Pit and Pia, against the rice blast fungus Magnaporthe oryzae and facilitates OsRac1 activation in vitro and in vivo.

在前期研究中发现，GTPase OsRac1参与了植物免疫过程，并且鉴定到了一个R蛋白Pit和OsRac1互作。 Pit参与了水稻对稻瘟病的免疫过程。 OsRac1位于Pit的下游，影响ROS的产生和细胞死亡。

2019年8月6日 · In this study, we demonstrate that OsRac1 Rho-like GTPase from plants (ROP GTPase), an important signaling protein, promotes rice grain yield at least in part through its promotion of grain size.