Impaired bone formation in ovariectomized mice reduces implant …
2017年9月14日 · Specifically, 12 week-old C57BL/6J mice underwent OVX/SHM surgery; 9 weeks after we inserted special metal-ceramics implants into the 6 th caudal vertebra and we …
Mechanical competence of ovariectomy-induced compromised …
2015年6月1日 · OVX caused a marked deterioration of the trabecular and cortical bone micro-structure, manifested as a considerable decrease in Ct.Th (−9%), BV (−52.6%), BV/TV …
JCI - Ovariectomy induces bone loss via microbial-dependent …
Here, we show that ovariectomy (ovx) expanded intestinal Th17 cells and TNF + T cells, increased their S1P receptor 1–mediated (S1PR1-mediated) egress from the intestine, and …
小鼠卵巢摘除模型OVX（骨质疏松）构建细节 - 知乎
小鼠卵巢摘除（ovariectomy，简称ovx）是一个较成熟的动物模型，通过双侧 卵巢摘除术 可以成功建立模拟雌激素缺乏而导致的骨质疏松动物模型。 卵巢所在位置 图源网络
PTH (1–34) treatment and/or mechanical loading have different ...
2020年6月1日 · Recombinant parathyroid hormone [1–34] (PTH (1–34)) is the basis of two FDA-approved bone anabolics prescribed for treatment of OP and associated bone...
Quercetin ameliorates bone loss in OVX rats by modulating the ...
2024年7月30日 · Micro-CT and HE staining analyses revealed that ABX intervention could effectively mitigate bone loss and restore bone microstructure in OVX rats (Fig. 7 A-E), which …
脊椎蛋白2对BMSCs成骨分化及卵巢去势小鼠骨代谢的作用研究
Micro-CT 检测示，与假手术组相比，OVX组Tb.Th、Tb.N和BV/TV降低，而Tb.Sp增高（P <0.05）；经Rspo2干预后，除Tb.Th外OVX+Rspo2组上述指标均得到改善（P <0.05）。 …
Impaired bone healing pattern in mice with ovariectomy-induced ...
2011年6月1日 · 3-month-old female C57BL/6 mice were randomly divided into an ovariectomy group (OVX) and a sham-operated group (Sham). At 6 weeks post-surgery, 7 mice from each …
去卵巢小鼠股骨微结构的动态变化研究 - tmmu.edu.cn
本研究以C57小鼠为实验动物，通过双侧卵巢摘除术诱导骨质疏松模型，模拟绝经后不同时期，应用micro-CT扫描和骨组织切片染色技术，观察术后不同时间点的骨量和骨组织形态学变化，旨 …
Corylifol A protects against ovariectomized-induced bone loss and ...
2023年2月20日 · This study found that CA prevented estrogen-deficiency-induced bone loss and suppressed osteoclastogenesis in ovariectomized (OVX) mice by inhibiting intracellular …