In cellular biology, P-bodies, or processing bodies, are distinct foci formed by phase separation within the cytoplasm of a eukaryotic cell consisting of many enzymes involved in mRNA turnover. [1] P-bodies are highly conserved structures and have been observed in somatic cells originating from vertebrates and invertebrates , plants and yeast .

细胞质加工小体或称P小体（英文中书写为Cytoplasmic processing bodies或P-bodies），通过浓缩细胞质中的酶参与mRNA的更新，同时屏蔽了众多不需要翻译的mRNA链使它们远离翻译蛋白。

Processing bodies (P-bodies) are cytoplasmic ribonucleoprotein (RNP) granules primarily composed of translationally repressed mRNAs and proteins related to mRNA decay, suggesting roles in post-transcriptional regulation. P-bodies are conserved in eukaryotic cells and exhibit properties of liquid droplets.

2018年1月30日 · Processing bodies (P-bodies) are cytoplasmic ribonucleoprotein (RNP) granules primarily composed of translationally repressed mRNAs and proteins related to mRNA decay, suggesting roles in post-transcriptional regulation. P-bodies are conserved in eukaryotic cells and exhibit properties of liquid droplets.

RAP55, Ge-1 and GW182 are markers of P bodies in multicellular organisms and are essential for P-body integrity, because their depletion leads to P-body loss 12,13,14,18.

处理小体（英语：P-bodies；全名processing bodies，其他名称还有GW-bodies与Dcp bodies）是一种发现于真核细胞内的颗粒（granule）构造，于哺乳动物细胞中的大小约100到300nm。

Polysomes, stress granules and processing bodies: a dynamic triumvirate controlling cytoplasmic mRNA fate and function. 图2. 植物细胞质mRNA 翻译，储存和降解概览. 细胞质mRNA经历活性翻译形式的 多聚核糖体 ，在受损或翻译抑制前会保持翻译活性状态（A）。

然而，问题仍然存在，对于RISC组分来说，P－bodies是否仅仅起到一个储存仓库的作用，或者RNAi是否在P－bodies上发生。 两个研究小组在探讨这个关键问题上运用了不同的方式，而且指出，RISC组分和靶mRNA确实共定位在P－bodies上，因而，P－bodies是细胞内RNA干扰发生 ...

2018年8月1日 · P-bodies (PBs) are cytosolic RNP granules that are conserved among eukaryotic organisms. In the past few years, major progress has been made in understanding the biochemical and biophysical mechanisms that lead to their formation. However, whether they play a role in mRNA storage or decay remains actively debated.

2024年11月7日 · Here, we investigate how P-bodies (PBs) evolve during cell-cycle progression in HEK293 cells. PB purification across the cell cycle uncovers widespread changes in their RNA content, partly uncoupled from cell-cycle-dependent changes in RNA expression.