Pathology Outlines - Staging-oropharynx & hypopharynx
Nov 21, 2019 · Oral cavity and oropharynx - Pathologic TNM staging of HPV mediated (p16+) oropharynx, oropharynx (p16-) and hypopharynx cancer (AJCC 8th edition)
Pathology Outlines - HPV associated SIL
Jan 6, 2021 · Essential features Precursor lesion of HPV associated vulvar carcinoma p16 positivity in block type pattern (strong diffuse nuclear or nuclear / cytoplasmic staining) Harbors clinically undetected carcinomas in up to 20% of cases (J Gynecol Oncol 2017;28:e27)
Pathology Outlines - Serous carcinoma
Jan 30, 2020 · The carcinoma shown in the image above, which involves the surface of an endometrial polyp, shows strong and diffuse positivity for p53 and p16. Which of the follow is true regarding the above carcinoma?
Pathology Outlines - Histology
May 7, 2021 · Squamocolumnar junction Cervical squamous epithelium Benign endocervical glands Dilated endocervical glands Normal cervical squamous p16 IHC Normal endocervical p16 IHC
Pathology Outlines - Stains & CD markers
Immunostains, routine stains and CD markers at PathologyOutlines.com
HPV associated cervical squamous cell carcinoma
Dec 11, 2023 · HPV associated cervical squamous cell carcinoma is an invasive epithelial tumor composed of neoplastic cells with varying degrees of squamous differentiation
Pathology Outlines - Tuboendometrioid metaplasia
Jan 25, 2024 · p16 is considered to be negative or only focally positive or show a mosaic pattern in tubal metaplasia (Adv Anat Pathol 2006;13:8, Cell Oncol 2007;29:37), useful to differentiate from high grade CIN and invasive cervical carcinomas that are diffusely positive
Pathology Outlines - HPV associated squamous cell carcinoma-vulva
Apr 2, 2024 · Board review style answer #1 D. p16. IHC for p16 shows highest specificity and sensitivity for HPV association. Answers A, B, C and E are incorrect because they are not relevant for verification of HPV association. Comment Here Reference: HPV associated squamous cell carcinoma-vulva
Pathology Outlines - Nasopharyngeal carcinoma
Dec 15, 2020 · Usually nonkeratinizing and shares certain histologic similarities Over 85% are p16 + and HPV + but negative for EBV, compared with nasopharyngeal carcinomas that are commonly related to EBV In the rare incidence of HPV related nasopharyngeal carcinoma, radiologic correlation to determine the location of the primary tumor is needed ...
Pathology Outlines - p40
Jun 13, 2022 · Invasive squamous cell carcinoma, poorly differentiated Ancillary studies: The malignant cells are diffusely positive for cytokeratin 5/6, p40 and p16 and are negative for cytokeratin 7, supporting the diagnosis.