The partial pressure of oxygen in the blood at which the hemoglobin is 50% saturated, typically about 26.6 mmHg (3.5 kPa) for a healthy person, is known as the P 50. The P 50 is a …

2015年8月6日 · In the ABG machine, this value is extrapolated from the measured PaO2 and sO2. It is represented as p50, in contrast to the p50(st) which is an idealised value calculated …

A pathological shift in the oxyhemoglobin curve (ODC) was previously described through the analysis of p50, intended as the oxygen tension at which hemoglobin is saturated by oxygen at …

2020年5月28日 · Oxygen tension at 50% haemoglobin saturation (P 50), which reflects the degree of peripheral oxygen offloading and tissue oxygenation, plays an important role in the …

2021年8月24日 · The most important parameters for characterizing the nonlinear, sigmoidal shape of the ODC are the P50 value (= O 2 partial pressure, PO 2, at which 50% of Hb is …

2017年4月16日 · This positive cooperativity is responsible for the ODC’s sigmoidal shape. A PO2 of ~27 mmHg in healthy adults corresponds to ~50% hemoglobin saturation (red curve). This …

2020年10月9日 · Oxygen affinity to haemoglobin is indicated by the p50 value (pO 2 at 50% O 2 Hb) and critically determines cellular oxygen availability. Although high Hb-O 2 affinity can …

What is the P50 of foetal haemoglobin? The curve has a sigmoid shape very similar to the normal ODC for adult haemoglobin but slightly left shifted. The P50 is lower at about 18 mmHg. …

The p50 value is the PO 2 (mmHg) at which hemoglobin is 50% oxygen saturated. The ODC measured at 37°C and pH 7.4 depends on cytosolic conditions (2,3 DPG) and type of …

2025年2月13日 · The right shifted ODC of SCD has been thought to result in abnormally low sO 2, even when pO 2 is normal. SCD patients do have elevated p50, indicating reduced Hb …