MMP-2 and p53 alterations were evaluated on 80 malignant, 30 benign ovarian tumors, and 62 metastatic lesions by using HRM method for mutations in p53 gene and by using RT-PCR for …

2009年12月1日 · MMP-2 transcriptional regulation is stimulated by EGF through several binding sites and transcription factors including p53; C/EBPɛ and −λ, AP-2 α and- γ and SP-1 and -4, …

We have recently published that p53 is involved in MMP-2 regulation and trophoblast invasion by EGF [52]. p53 was among the transcription factors increased under EGF stimulation (p53, SP …

Western blot analysis revealed that the expression of p53 and MMP-2 protein in the tumor tissue after chemotherapy was significantly decreased. The positive expression of p53 and MMP-2 in …

2013年2月15日 · p53 is a well-known tumor suppressor gene, and its mutational inactivation is seen in many human cancers. Ki-67 is a marker of mitotic activity in cells. Matrix …

Gao et al. (2019) reported that RNF128 regulates ESCC invasion and metastasis by interacting with p53 and EGFR in the EGFR/MAPK/MMP-2 pathway [120]. Moreover, Chen et al. …

结果 VEGF、p5 3、MMP 2阳性表达与IMVD和淋巴结转移等相关 (P <0 .0 5 )。 结论 VEGF、P5 3及MMP 2可能均参与了NSCLC的新血管生成并促进肿瘤转移, 其检测可作为判断NSCLC转移 …

Correlation of p53, Ki-67, MMP-2 and MMP-9 over-expression with conventional pathological parameters and patient survival was examined. Results: p53 over-expression was significantly …

2018年7月20日 · The results showed that the protein expression of p53 and MMP-2 in tumor tissues of elderly patients with lung cancer after chemotherapy were significantly decreased, …

MMP-17和-25有一个糖基磷脂酰肌醇（GPI）锚。 MMP-23可通过其II型信号锚处于潜在的非活性形式，并且具有富含半胱氨酸和免疫球蛋白样脯氨酸的区域（图1）。