The expression levels of MMP-9 and P53 in serum were detected by fluorescence quantitative Real-Time Polymerase Chain Reaction (RT-PCR). The diagnostic value of MMP-9 and P53 in …

Because of p53 overexpression in trophoblastic cells, and its potential role in regulating MMP-2 and MMP-9 expression in different cell lines, we hypothesized that the expression of MMP-9 …

There was a positive correlation between the expression of MMP-9 and p53 proteins (p<0.05), suggesting that the two proteins likely played a synergistic role in the development and …

2021年6月14日 · In this review, we discuss the functional relationships between galectin-7, p53 and MMP-9 and reconcile some apparently contradictory observations. A better understanding …

2005年5月16日 · Using MMP inhibitors and MMP-specific small interfering RNA, we show that MMP function confers protection from PKC/p53-induced apoptosis and identify the protective …

Objectives: p53 mutations and high protein expression are associated with adverse prognosis in several lymphoma subtypes. Matrix metalloproteinase-9 (MMP-9) has also been found to …

MMP-9 can cleave many extracellular matrix (ECM) proteins to regulate ECM remodeling. It can also cleave many plasma surface proteins to release them from the cell surface. MMP-9 has …

2013年2月15日 · The level of p53, MMP-2 and 9 expressions at IF of the lesions can be helpful in the differentiation of VC and SCC and their histological grading. Among the surveyed markers, …

2024年7月17日 · Mechanistically, AGEs interact with RAGE to induce the overexpression of GADD45α through a p53-dependent pathway, leading to GADD45α recruitment to the …

含氨基末端前肽PRCGXPD的MMP-9作为酶原合成和分泌，前肽PRCGXPD中半胱氨酸巯基与活性部位的锌螯合，使MMP-9保持潜伏形式。 MMP-9的潜伏形式主要以两种形式存在，一种是单 …