2024年12月25日 · Complete information for RELA gene (Protein Coding), RELA Proto-Oncogene, NF-KB Subunit, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium

2024年12月25日 · This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex.

Showing of 3,180 Results for p65 Search Time: 0 ms. Export Show: Symbol Description Category UniProt ID GIFtS GC id Score; 1: RELA: RELA Proto-Oncogene, NF-KB Subunit: Protein Coding: Q04206: 64: GC11M065653: 36.27: 2: NFKB1: Nuclear Factor Kappa B Subunit 1: Protein Coding ... Gene symbols for p65.

Showing of 8 Results for P65 Search Time: 0 ms. Export Show: Symbol Description Category UniProt ID GIFtS GC id Score; 1: RELA: RELA Proto-Oncogene, NF-KB Subunit: Protein Coding: Q04206: 64: GC11M065653: 6.42: 2: GORASP1: Golgi Reassembly Stacking Protein 1 ... Gene symbols for P65.

2024年12月25日 · NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52.

2024年12月25日 · This gene encodes a member of the synaptotagmin protein family. The synaptotagmins are integral membrane proteins of synaptic vesicles that serve as calcium sensors in the process of vesicular trafficking and exocytosis.

2024年12月25日 · NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable ...

2024年12月25日 · Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL (RELA/p65 and NFKB1/p50) dimers in the cytoplasm by masking their nuclear localization signals (PubMed:1493333, 36651806, 7479976).

2024年12月25日 · NFKBIE (NFKB Inhibitor Epsilon) is a Protein Coding gene. Diseases associated with NFKBIE include St2 Diffuse Large B-Cell Lymphoma and N1 Diffuse Large B-Cell Lymphoma. Among its related pathways are TNFR1 Pathway and 4-1BB Pathway. An important paralog of this gene is BCL3.

2024年12月25日 · This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II.