Proteintech's Mouse Monoclonal PD-1/CD279 antibody is validated in WB, IHC, IF-P, ELISA and shows reactivity with human, mouse, rat, pig samples.

PD1是一种在活化的 T 细胞中表达的免疫抑制受体，参与调节 T 细胞功能，在诱导和维持对自身的免疫耐受中起关键作用。 PD-L1 可结合活化T细胞表面的B7.1和PD1 降低细胞毒性。 PD1/PD-L1 相互作用可以通过限制自身的免疫反应调节自身免疫。 PD1/PD-L1通路与适应性免疫抑制的发展有关，其中 PD-L1的过表达能够响应抗肿瘤活性。 PD1介导的抑制通路被肿瘤利用来减弱抗肿瘤免疫，并逃避免疫系统监控，从而促进肿瘤存活。 通过抑制PD1介导的信号通路，可以介导耗尽 …

Choose from 1 of 295 PD-1 (CD279) antibodies, which have been validated in experiments with 1871 publications and 1939 images featured in our data gallery. Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications.

The programmed cell death 1 protein (PD-1, PDCD1, CD279) is a member of the CD28 family of immunoreceptors that regulate T cell activation and immune responses (1-3). The PD-1 protein contains an extracellular Ig V domain, a transmembrane domain, and a cytoplasmic tail that includes an immunoreceptor tyrosine-based inhibitory motif (ITIM) and ...

Programmed cell death protein 1 (PDCD1)靶点介绍助您了解其蛋白功能，蛋白定位，蛋白特性，蛋白表达及异构体和翻译后修饰。 同时列举了实用的IHC及WB实验小贴士，助您实验成功。

Invitrogen Anti-PD-1 Polyclonal, Catalog # PA5-20350. Tested in Western Blot (WB) and Immunohistochemistry (Paraffin) (IHC (P)) applications. This antibody reacts with Human, Mouse, Rat samples. Supplied as 100 µg purified antibody (1 mg/mL).

Choose from 1 of 295 PD-1 (CD279) antibodies, which have been validated in experiments with 1871 publications and 1939 images featured in our data gallery. Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications.