2021年9月29日 · Here we report four cryo-electron microscopy structures of LHCGR: two structures of the wild-type receptor in the inactive and active states; and two structures of the constitutively active mutated receptor.

RCSB Protein Data Bank (RCSB PDB) enables breakthroughs in science and education by providing access and tools for exploration, visualization, and analysis of: These data can be explored in context of external annotations providing a structural view of biology. 3D visualization for PDB structures and ligand binding sites.

Luteinizing hormone subunit beta also known as lutropin subunit beta or LHβ is a polypeptide that in association with an alpha subunit common to all gonadotropin hormones forms the reproductive signaling molecule luteinizing hormone.

方法（1）使用pymol的方法 pymol的下载安装使用方法在教程已经叙述过了 提取该蛋白质结构的所有序列 save 1ywt.fasta仅提取该蛋白质结构的特定chain的序列 save 1ywt.fasta, chain A 方法（2）使用网页在线数据库…

Lutropin-choriogonadotropic hormone receptor, LH/CG-R, Luteinizing hormone receptor, LHR, LSH-R

HH23 male patients have normal sexual differentiation, reduced or absent Leydig cells, reduced or absent spermatogenesis, and absence of spontaneous puberty. Female patients exhibit normal pubertal development and menarche, followed by oligomenorrhea and anovulatory secondary amenorrhea. Showing features for natural variant.

PDB中的小分子配体可以粗略地分为“功能性 (functional)”（即可能在生物/生化角色中发挥作用的配体）和“非功能性 (non-functional)”两类。 功能性配体 包括辅因子 (co-factors)、激活剂 (activators)、抑制剂 (inhibitors)、底物 (substrates)、产物和中间体，以及这些的任何类似物，而 非功能性配体 通常是溶剂、盐、离子和结晶剂。 与其蛋白质或核酸靶标结合的配体的结构对于理解它们的相互作用方式、结合强度和选择性（Burley 2021）非常有用。 wwPDB化学组分字 …

2021年9月22日 · Here we report four cryo-electron microscopy structures of LHCGR: two structures of the wild-type receptor in the inactive and active states; and two structures of the constitutively active mutated...

2019年11月1日 · The β subunit of bovine luteinizing hormone (LH) was crystallized and its structure solved to 3.15 Å resolution by molecular replacement using human chorionic gonadotropin (hCG) β subunit as search model.

2021年7月31日 · Here we report four cryo-electron microscopy structures of LHCGR: two structures of the wild-type receptor in the inactive and active states; and two structures of the constitutively active mutated receptor.