Single‐cell experiments have clarified that pDC and pre‐cDC have often been previously analysed as a mixed population. DC subset specialization increases the range and flexibility of immune …

2018年6月14日 · 共同树突细胞祖细胞（CDPs）在骨髓中产生pre-pDC和pre-cDC。 pre-cDCs和分化的pDC在血液中循环并不断地补充淋巴器官和外周组织DC池。 Pre-cDC在外周组织分化 …

Plasmacytoid dendritic cells (pDCs) are innate immune sentinels that play important roles in immunity to infection and autoimmunity. This review by Boris Reizis highlights recent progress …

树突状细胞主要分为经典型树突状细胞（cDC）以及浆细胞样树突状细胞（pDC），多数的树突状细胞起源于共同DC前体（CDP）。 pDC将在骨髓中继续发育，而CDc则在外周分化 [5]。 另 …

This review summarises the latest advances in several aspects of plasmacytoid dendritic cell (pDC) biology, with a special focus on pDC heterogeneity, pDC development via the lymphoid …

Dendritic cells (DCs) develop from hematopoietic stem cells (HSCs) in a multistep process that begins in the bone marrow. Most DCs arise through a common DC progenitor (CDP) that …

2018年6月20日 · Plasmacytoid dendritic cells (pDCs) are type I interferon–producing cells with antigen-presenting potential. pDC populations are composed of transcriptionally and...

2019年5月28日 · Plasmacytoid dendritic cells (pDCs) and two major subsets of conventional dendritic cells (cDC1 and cDC2) have been identified in mice and humans as well as other …

2019年6月18日 · We found the transcriptional signature of a pDC precursor stage, defined here, in the IL-7Rα + common lymphoid progenitor population and identified Ly6D, IL-7Rα, CD81 …

Interferon-producing plasmacytoid dendritic cells (pDC) are a specialized branch of the dendritic cell (DC) family, and their differentiation in mice is closely linked to that of conventional DC …