
Protein disulfide-isomerase - Wikipedia
Protein disulfide isomerase (EC 5.3.4.1), or PDI, is an enzyme in the endoplasmic reticulum (ER) in eukaryotes and the periplasm of bacteria that catalyzes the formation and breakage of …
The human protein disulfide isomerase gene family
2012年7月5日 · Enzyme-mediated disulfide bond formation is a highly conserved process affecting over one-third of all eukaryotic proteins. The enzymes primarily responsible for …
The Protein Disulfide Isomerase Family: from proteostasis to ...
2020年2月1日 · Oxidative folding and chaperoning in the ER are assisted by ~20 PDI family members. PDIs recognize and act on clients via conserved interdomain flexibility. Exactly how …
Functions and mechanisms of protein disulfide isomerase family …
Herein, we review recent research advances on PDIs, vis-à-vis their expression, functions, and molecular mechanisms in supporting cancer growth with special emphasis on the anterior …
A structural overview of the PDI family of proteins
2010年8月26日 · Analysis of the structures reveals common features shared by several of the best known PDI family members, and also unique features related to substrate and partner …
The human protein disulfide isomerase gene family - PMC
Enzyme-mediated disulfide bond formation is a highly conserved process affecting over one-third of all eukaryotic proteins. The enzymes primarily responsible for facilitating thiol-disulfide …
The human PDI family: Versatility packed into a single fold
2008年4月1日 · The enzymes of the protein disulfide isomerase (PDI) family are thiol–disulfide oxidoreductases of the endoplasmic reticulum (ER). They contain a CXXC active-site …
The human protein disulphide isomerase family: substrate …
This review discusses recent advances in our understanding of the human PDI family of enzymes and focuses on their functional properties, substrate interactions and some recently identified …
The protein disulfide isomerase family: key players in health …
2012年4月15日 · In this review, the importance of PDI in health and disease will be examined, using examples from the fields of lipid homeostasis, hemostasis, infectious disease, cancer, …
The Protein Disulfide Isomerase Family: from proteostasis to ...
In mammalian cells, nearly one-third of proteins are inserted into the endoplasmic reticulum (ER), where they undergo oxidative folding and chaperoning assisted by approximately 20 members …
- 某些结果已被删除