Polyclonal Antibody for studying PDK1. Validated for WB. Available in 2 sizes. Highly specific and rigorously validated in-house, PDK1 Antibody (CST #3062) is ready to ship.

Starvation increases islet PDK activity (PMID:11723055). PDK1 has 2 isoforms with the MW of 49 and 52 kD, and a 28aa-transit-peptide in the N-terminal can be removed in the mature form. …

2023年6月6日 · Our study reveals dynamic conformations of full-length PDK1 in which the location of the linker and the PH domain relative to the catalytic domain determines the …

Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues around Ser241 of human PDK1. Phosphoinositide-dependent …

Phosphoinositide-dependent protein kinase 1 (PDK1) plays a central role in many signal transduction pathways (1,2) including the activation of Akt and the PKC isoenzymes p70 S6 …

Serine/threonine kinase required for embryonic development. Inhibits apoptosis. Acts in the insulin receptor transduction pathway which regulates cell growth and organ size, by phosphorylating …

2024年12月25日 · PDK1 (Pyruvate Dehydrogenase Kinase 1) is a Protein Coding gene. Diseases associated with PDK1 include Pyruvate Dehydrogenase E3-Binding Protein Deficiency and …

We provide genetic evidence that PDK1 is essential for mouse embryonic development, and regulates cell size independently of cell number or proliferation, as well as insulin’s ability to …

Phospho-PDK1 (Ser241) Antibody detects PDK1 only when phosphorylated at Ser241. Human, Mouse, Rat. Polyclonal antibodies are produced by immunizing animals with a synthetic …

2021年12月21日 · PDK1 is believed to form PDK1-AKT1 and PDK1-PKCα heterodimers stabilized by a PDK1-interacting fragment (PIF) interaction between the PDK1 PIF pocket and …