2023年4月27日 · Tumoricidal photodynamic (PDT) and photothermal (PTT) therapies harness light to eliminate cancer cells with spatiotemporal precision by either generating reactive oxygen species or increasing temp...

2003年5月1日 · At present, PDT is being tested in the clinic for use in oncology — to treat cancers of the head and neck, brain, lung, pancreas, intraperitoneal cavity, breast, prostate and skin. How does PDT...

2019年7月26日 · Immunogenic cell death (ICD)-associated immunogenicity can be evoked through reactive oxygen species (ROS) produced via endoplasmic reticulum (ER) stress. In this study, we generate a double...

2024年1月17日 · LLI-based immunogenic PDT and neutrophil-targeting immunotherapy synergistically boost the anti-PD-1 treatment to elicit potent TME and systemic antitumor immune response with abscopal effects. In conclusion, LLI holds great potential for GC immunotherapy.

2022年6月17日 · Under near-infrared (NIR) irradiation, ER-targeting photodynamic therapy (PDT) induced by Par-ICG-Lipo could promote the release of danger-signaling molecules (DAMPs) and tumor antigens (TAAs) in vivo, which significantly enhanced the immunogenicity in vivo and thus stimulates a strong antitumor immune response.

2020年7月1日 · Photodynamic therapy (PDT) is a promising alternative approach for effective cancer treatment, which can directly destroy local tumor cells due to the generation of cytotoxic singlet oxygen and reactive oxygen species (ROS) in the tumor cells. Intriguingly, PDT-mediated cell death is also associated with anti-tumor immune response.

2021年6月21日 · Photodynamic therapy uses a drug activated by light to kill cancer and other abnormal cells. Learn how photodynamic therapy works, about the types of cancer and precancers that is used to treat, and the benefits and drawbacks of this treatment.

2024年4月1日 · Photodynamic therapy (PDT) has been a promising therapeutic approach for oral squamous cell carcinoma (OSCC) on account of its ability to provoke immunogenic cell death (ICD) properties. However, unaggressive and intolerable immune responses hinder its tumor immunotherapy efficacy.

Photodynamic therapy (PDT) is a treatment that uses special drugs, sometimes called photosensitizing agents, along with light to kill cancer cells. The drugs only work after they have been activated or “turned on” by certain kinds of light. PDT may also be called photoradiation therapy, phototherapy, or photochemotherapy.

6 天之前 · Photodynamic therapy (PDT) is an innovative treatment that has recently been approved for clinical use and holds promise for cancer patients. It offers several benefits, such as low systemic toxicity, minimal invasiveness, and the ability to stimulate antitumor immune responses. For certain types of cancer, it has shown positive results with few side effects. However, PDT still faces some ...