不同剂量博来霉素诱导的肺纤维化大鼠模型比较
2024年11月19日 · Objective To compare the success rate and stability of rat pulmonary fibrosis (PF) models induced by intratracheal instillation of different doses of bleomycin (BLM). …
Reversal of bleomycin-induced rat pulmonary fibrosis by a ... - PubMed
2019年9月17日 · This study investigated the feasibility of HUMSC engraftment into rats with bleomycin (BLM)-induced PF to explore HUMSC therapeutic effects/outcomes. Methods: A …
miR-155-5p/FOXO3a promotes pulmonary fibrosis in rats by
Objective: Pulmonary fibrosis (PF) is regarded as progressive lung disease. miR-155-5p depletion exerts anti-fibrotic effects in silicotic mice. This study explored the effect and possible …
Multi-omics study reveals Shuangshen Pingfei formula regulates …
2024年12月25日 · In this study, the effect of SSPF was evaluated by applying a rat model of PF caused by intratracheal drip bleomycin. To characterize the molecular changes related to PF …
Assessment of progression of pulmonary fibrosis based on …
2024年3月15日 · The main purpose of this study was to explore the changes of biomarkers in different developmental stages of bleomycin-induced pulmonary fibrosis (PF) in rats via …
Network pharmacology and experimental verification to decode …
2024年6月24日 · In the present study, the network pharmacology method was used for identification of the potential targets of QFHXD for treating PF. The identified key targets were …
Comparative Proteomic Analysis of Bleomycin-induced …
This study investigated differentially expressed proteins associated with the occurrence and development of PF in rat lung tissue with bleomycin-induced PF. Methods: Sixteen Sprague …
Frontiers | Regulation of idiopathic pulmonary fibrosis: a cross-talk ...
2024年9月24日 · Pulmonary fibrosis (PF) is a highly complex and challenging disease affecting the respiratory system. Patients with PF usually have an abbreviated survival period and a …
Comparison of reversal of rat pulmonary fibrosis of nintedanib ...
2020年11月30日 · The present study compared the effects of antifibrotic medications, pirfenidone, and nintedanib, with transplantation of human umbilical mesenchymal stem cells (HUMSCs) in …
Pharmacodynamic and pharmacokinetic assessment of pulmonary ...
2017年6月14日 · Twelve male SD rats (180–220 g) were acclimatized for 7 days and then randomly divided into two groups, the control group and the PF group. The rats in the PF …