Quantitation of Plasma Proteins to Predict Taxane-Induced …
2025年1月31日 · Purpose: Taxane-induced peripheral neuropathy (TIPN) is a dose-limiting toxicity of paclitaxel in patients with cancer. TIPN prediction is challenging although patients …
Impact of persistent peripheral neuropathy on health-related …
2022年8月9日 · We explored the impact of persistent sensory and motor taxane-induced peripheral neuropathy (TIPN) symptoms on health-related quality of life (HRQL) among early …
多发性骨髓瘤周围神经病变诊疗中国专家共识 (2015年) - 中华内科 …
TiPN的发生可能与沙利度胺抗血管新生作用相关，致使神经纤维缺血、TNFα表达下调、NF–κB通路阻断，进而诱发神经纤维的损伤、促发神经细胞死亡等 [16]。 其他药物，包括长春新碱相 …
Incidence, description, predictors, and consequences of persistent ...
2024年3月1日 · Recent findings: Studies show varying rates of TIPN persistence, with an estimated 30-40% and 40-60% resolving by 1- and 3-year post-treatment. TIPN in the feet and …
A Multimodal Approach to Discover Biomarkers for Taxane …
Taxane-induced peripheral neuropathy (TIPN) occurs in up to 70% of patients, impacting quality of life both during and after treatment. TIPN typically manifests as tingling and numbness in …
【科研背后】提高疗效与改善生活质量并重——GM1显著降低紫杉 …
2019年8月29日 · 紫杉类药物引起的周围神经毒性（tipn） 然而，紫杉类药物引起的周围神经毒性（Taxane-induced peripheral neuropathy，TIPN）是剂量限制性毒性，主要表现为肢端麻木、 …
Risk prediction model for taxane-induced peripheral neuropathy (TIPN …
2024年5月29日 · The primary endpoint was the occurrence of TIPN, defined as an increase of >8 points over baseline in the EORTC QLQ-CIPN20 sensory subscale score at any follow-up …
Quantitation of Plasma Proteins to Predict Taxane-Induced …
2025年1月31日 · Taxane-induced peripheral neuropathy (TIPN) is a dose-limiting toxicity of paclitaxel in patients with cancer. TIPN prediction is challenging although patients with higher …
Taxane-induced neuropathy: How serious is this problem for
Taxane-induced peripheral neuropathy (TIPN) is a common toxicity and confers significant morbidity with no validated therapies. Literature detailing TIPN is inconsistent in reporting its …
中国多发性骨髓瘤周围神经病诊疗专家共识 - 百度文库
多发性骨髓瘤周围神经病变（MMPN）是指在多发性骨髓瘤疾病过程中出现任何形式的周围神经 病变（如损伤、炎症或变性），临床出现感觉神经、运动神经及自主神经受损的症状或体征 1。 …